Project Manager, Change Management, IT Project Manager

Candidates must have Pharmaceutical Manufacturing experience - supporting IT systems.

REMOTE with occasional onsite visits to MFG plants per quarter.

Required to have GMP and Pharma experience.

Candidates should have high level of exec comm skills, high level of organizational skills, ability to run 6+ projects/work streams simultaneously. Strong experience working on Smartsheets.

12+ Month W2 Contract

Must sit in Central or East Coast Time Zone

Preference for candidates local to New Albany, OH

Travel: Approximately 4-8 trips to New Albany, Ohio per year.

Milestone is seeking an experienced Senior Program Manager with pharmaceutical, life sciences, or manufacturing technology experience to lead a portfolio of strategic digital transformation initiatives across manufacturing operations, operational technology (OT), infrastructure, cybersecurity, analytics, and AI-driven solutions.

This individual will be responsible for managing multiple interconnected programs and work streams, providing leadership across business, manufacturing, engineering, IT, cybersecurity, and vendor teams. The ideal candidate is a hands‑on program leader who can establish governance, drive accountability, manage budgets, mitigate risks, and ensure successful execution of complex enterprise initiatives.

This role requires exceptional stakeholder management skills, executive communications experience, and the ability to align diverse teams toward common business outcomes while operating in a highly regulated manufacturing environment.

The Senior Program Manager will provide leadership and oversight for the following key initiatives:

• Lead enterprise deployment and adoption of PI System capabilities within manufacturing environments.
• Coordinate integration efforts between operational technology, manufacturing systems, and business applications.
• Establish program plans, governance structures, reporting cadences, and implementation roadmaps.
• Drive stakeholder alignment and adoption strategies across manufacturing sites.

• Lead enterprise-wide passwordless authentication initiatives in partnership with cybersecurity and infrastructure teams.
• Manage implementation plans, risk mitigation strategies, user readiness, and adoption activities.
• Coordinate cross-functional resources to ensure successful rollout and compliance with security standards.

• Oversee implementation and enhancement of Plant Apps capabilities supporting manufacturing operations.
• Partner with business and plant leadership to prioritize requirements and deliver operational improvements.
• Manage vendor engagement, project dependencies, and deployment activities.
• Lead deployment of AI-enabled Equipment Copilot solutions.
• Coordinate pilot programs, business adoption, requirements gathering, and scaling efforts.
• Drive integration with existing manufacturing and operational technologies.
• Measure and report business value, operational efficiencies, and adoption metrics.

• Lead initiatives focused on operational reporting, metrics, dashboards, visualization tools, and analytics capabilities.
• Partner with business leaders to define KPIs and performance measurement frameworks.
• Drive transparency and data-driven decision-making across manufacturing operations.

• Oversee deployment and lifecycle management of manufacturing peripheral hardware including scanners, printers, mobile devices, and shop-floor technology.
• Manage procurement, vendor coordination, deployment planning, logistics, and site readiness activities.
• Ensure minimal disruption to manufacturing operations during implementations.

• Manage a portfolio of complex, cross-functional programs and projects simultaneously.
• Develop and maintain integrated program plans, schedules, milestones, dependencies, and resource forecasts.
• Establish program governance, steering committees, and executive reporting processes.
• Drive successful delivery of strategic initiatives through effective planning and execution.

• Serve as primary point of contact for executive sponsors, business leaders, and project stakeholders.
• Facilitate governance meetings, leadership reviews, and steering committee sessions.
• Build strong working relationships across business, manufacturing, engineering, cybersecurity, infrastructure, and vendor teams.
• Communicate program status, key…