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Principal Programmer Analyst

Job in Harrisburg, Dauphin County, Pennsylvania, 17101, USA
Listing for: GSK
Full Time position
Listed on 2026-10-15
Job specializations:
  • Software Development
    Software Engineer
Job Description & How to Apply Below
Principal Programmer Analyst We are seeking a Principal Programmer Analyst to join our Clinical Programming team, contributing to pipeline delivery across complex and pivotal studies. This role operates within an agile, squad-based environment, where you will lead study delivery, collaborate with cross-functional teams, and act as a technical mentor to ensure high-quality and timely outputs. Working closely with stakeholders across clinical, statistical, and operational functions, you will play a key role in bridging scientific requirements with technical solutions, supporting the successful execution of clinical development programmes within a global setting.

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practices; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSKIn this role you will Independently lead programming activities for one or more studies, ensuring development, maintenance, and validation of complex analysis packages

Foster quality assurance by ensuring programming activities adhere to standards such as Good Programming Practices and CDISCMentor junior programmers by providing guidance and support in technical programming tasks and industry best practices

Lead programming support for regulatory interactions (e.g., EMA, FDA)
Identify gaps and inefficiencies and recommend and implement innovative solutions aligned with standards and best practices

Establish and uphold governance frameworks, identify risks early and devise mitigation plans, ensuring timely escalation

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

Bachelor’s degree in Mathematics, Computer Science, or a related discipline

Five or more years if experience with at least one programming language and ability to evaluate and select appropriate tools or languages for specific tasks

Three or more years of experience working in the pharmaceutical/biotech industry with advanced understanding of clinical trials and therapeutic areas, applied to enhance programming outputs and decision-making

Experience leading discussions on programming strategies, displays, and custom programs

Experience implementing principles of governance, quality control, and compliance with regulatory requirements and programming standards

Preferred Qualifications:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

Experience guiding others in the use of Artificial Intelligence/Machine Learning (AI/ML) tools or applying these tools to improve efficiency

Experience contributing to internal technical discussions, forums, or external technical organizations

Application of critical thinking to implement standards and collaborate with stakeholders where deviations are required

Ability to articulate complex technical information effectively to both technical and non-technical stakeholders

Experience contributing to department strategies and key technical initiatives through working groups or sub-teams

Demonstrated networking and collaboration across departments, divisions, and external partners

Experience facilitating integration across matrix teams and contributing to planning and execution of programming activities

Experience guiding teams and individuals, fostering continuous improvement, collaboration, and…
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