Manager, Clinical Operations

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and Med Tech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

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As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:
R&D Operations
Job Sub Function:
Clinical Trial Project Management
Job Category:
People Leader
All Job Posting Locations:
High Wycombe, Buckinghamshire, United Kingdom
Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at

We are searching for the best talent for a Manager, Clinical Operations, United Kingdom. This individual will be responsible for the operational management and successful execution of all phases of clinical trials within their assigned therapeutic area(s). Key responsibilities include resource allocation, maintaining adherence to timelines and budgets, and ensuring compliance with relevant Standard Operating Procedures (SOPs), policies, Health Care Compliance (HCC), and local regulatory requirements.

The head office is based in High Wycombe, Buckinghamshire, UK, moving to Maidenhead in October 2026. This position offers a hybrid working model, requiring three days on-site each week.

Purpose:

The Manager, Clinical Operations serves as a key line leader, guiding and supporting a diverse team of professionals-including Local Trial Managers (LTM), Site Managers (SM) and/or other Global Clinical Operations (GCO) staff. This leader is responsible for overseeing their team's performance, supporting professional growth, providing training, managing project assignments, and ensuring workload balance. They help resolve issues and challenges within the team while aligning local objectives with the broader organizational goals.

They may mentor less experienced Functional Managers (FM) and oversee cross-therapy and cross-border activities when needed.

Additionally, the Manager, Clinical Operations drives innovation and process improvements within their therapeutic area, country, and across GCO/Global Development, aiming to enhance efficiency and impact. Overall, they create a supportive, engaging environment that encourages progress and team success.

This role is supporting our Oncology business, but may support other therapeutic areas as required, in line with business needs.

Are you ready to join our team? Then please read further!

You will be responsible for:

• Providing line management to direct reports, including setting goals and objectives, conducting performance evaluations, and supporting talent development.
• Evaluating and forecasting resource needs for the assigned portfolio and/or other specific areas of responsibility, in collaboration with local GCO management.
• Ensuring the deployment of the One Delivery Model through collaboration and oversight of vendors.
• Being accountable for the acquisition of new talent and the ongoing development of human resources.
• Guiding direct reports in issue resolution and communication with involved stakeholders.
• Leading organizational changes and effectively communicating shifts in priorities as necessary.
• Reviewing and approving expenses in accordance with company policies.
• Demonstrating leadership behaviors aligned with J&J Leadership Imperatives.
• Fostering an environment that encourages sharing of ideas, information, and…