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Lead, Manufacturing Systems Engineer; MES

Job in Hillsboro, Washington County, Oregon, 97104, USA
Listing for: Entegris
Full Time position
Listed on 2026-01-12
Job specializations:
  • Manufacturing / Production
    Systems Engineer, Manufacturing Engineer
Job Description & How to Apply Below
Position: Lead, Manufacturing Systems Engineer (MES)

Job Title

Lead, Manufacturing Systems Engineer (MES)

Job Description

Lead. Inspire. Innovate. Define Your Future.

Not everyone who works for a global company shares the same background, experiences and perspectives. We leverage the differences of our employees to bring new ideas to the table. Every employee throughout the company is encouraged to share input on projects and initiatives. Our decision‐making process is truly a collaborative effort as we realize there are leaders at every level of the organization.

We put our values at the core of how we operate as an organization — not just when it’s convenient, but in a lasting and meaningful way. We want the time and energy you spend here to have a positive impact on your life inside and outside of the office.

The Role

As a Lead, Manufacturing Systems Engineer on the Digital Manufacturing team, you are a fully qualified, experienced professional responsible for resolving a wide range of issues related to our core manufacturing systems, including MES, SPC, and LIMS. This journey‑level role is central to enabling data‑driven operations, where you will work independently to ensure system reliability and scalability, devising creative solutions to support manufacturing excellence across global sites.

What

You’ll Do
  • Actively champion digital manufacturing at the site, assessing circumstances and suggesting variations in approach to enhance safety, productivity, quality, and compliance.
  • Act as a subject matter expert in site products, technical processes, and business processes, advising others on difficult matters.
  • Work independently with manufacturing teams on problems of diverse scope, using your judgment and interpretation to ensure systems like MES, LIMS, and SPC meet business goals.
  • Keep manufacturing systems running smoothly by resolving a wide range of issues, evaluating identifiable factors to devise effective solutions and continuous improvement opportunities.
  • Partner with global teams to independently evaluate solutions and support the implementation of new digital capabilities at the site.
  • Serve as a key escalation point and site contact for digital manufacturing activities, providing Tier‑2/3 support for MES, SPC, and LIMS platforms.
  • Lead system configuration, integration, and validation efforts, adapting existing approaches to resolve issues across multiple manufacturing sites.
  • Develop and maintain documentation and SOPs to build the knowledge base for Tier‑0 and Tier‑1 support teams.
  • Lead or support User Acceptance Testing (UAT), training, and change management activities to ensure the successful adoption of new tools and processes.
  • Ensure compliance with regulatory, security, and quality standards in all system‑related activities, with your work being reviewed at critical points.
What We Seek
  • Bachelor’s degree in Engineering, Computer Science, or a related field; advanced degree or certifications in MES/LIMS/SPC systems preferred.
  • 6+ years of experience supporting or implementing MES in a manufacturing or life sciences environment. Experience with preferred platforms and LIMS, SPC systems is a plus.
  • Understanding of Manufacturing Operations Management principles and strategy.
  • Experience in operations of a 24/7 Manufacturing facility.
  • Experience with global system governance, vendor management, and cross‑functional collaboration.
  • Strong analytical and problem‑solving skills, with the ability to translate business needs into technical solutions.
  • Excellent communication and stakeholder management skills across global teams.
  • Experience with system validation, change control, and documentation in a regulated environment.
  • Experience with Camline, Ignition, Critical Manufacturing, Sample manager, Labware a Plus.
  • Experience with OT/Automation Platforms including Rockwell, GE, Siemens, Keyence a Plus.
What We Offer

Our total rewards package goes above and beyond just a paycheck. Whether you’re looking to build your career, improve your health, or protect your wealth, we offer generous benefits to help you achieve your goals.

  • $‑$ a year range with actual pay dependent on candidate overall skills for the role
  • Annual bonus eligible
  • Progressive paid time off policy that…
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