Director - DMPK

Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the UK, US, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services.

We're proud of the impact we make and just last year, we supported 887 discovery projects
, 1,100+ CMC programs
, and 1,397 clinical trials
across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers
. To learn more, visit

Our Hoddesdon campus comprises more than 5,000 m² of purpose-built R&D space and houses established Drug Discovery, Process Chemistry and Analytical Chemistry teams, alongside Drug Product Development and state-of-the-art GMP facilities. We offer a highly supportive and collaborative environment that enables our employees to develop and achieve their full potential.

The Integrated Drug Discovery (IDD) Services group at Pharmaron is responsible for leading and delivering drug discovery projects for our client partners. The team comprises scientific expertise and strategic leadership across medicinal chemistry, CADD, biology, DMPK and translational science. Combined with Pharmaron’s global research capabilities we design and deliver integrated programmes from target identification and hit finding through to IND filing.

Working closely with our partners we define strategy, coordinate execution across teams and with an AI enabled accelerated Design–Make–Test–Analyse cycles support the progression of projects and innovative medicines towards the clinic.

This Director in DMPK is a high-impact leadership role at the forefront of multi-modality drug discovery, where you will shape DMPK strategy, drive scientific excellence and deliver client programmes from target identification through to IND. Working across a global, AI-enabled platform, you will help accelerate innovative medicines towards the clinic.

With a rapidly expanding department and portfolio, our Drug Discovery DMPK function is seeking experienced scientific leaders with a passion for leading DMPK science and strengthening the capabilities of our research teams. As a Director in DMPK
, you will provide expert guidance and delivery across DMPK, ADME, modelling and PKPD science for integrated drug discovery projects. You will lead DMPK input into multidisciplinary project teams, work directly with client partners and collaborate internationally across Pharmaron to drive project progression and enhance our overall DMPK capabilities.

• Act as the frontline DMPK discipline contact, providing leadership and influence in the design of successful DMPK, PKPD, modelling and progression strategies for multiple drug discovery projects.
• Lead DMPK strategy from hit finding and lead optimisation through to candidate selection, nomination and IND-enabling activities.
• Work collaboratively within cross-disciplinary matrix teams and with client partners to support the design, identification and optimisation of candidate molecules.
• Develop and present scientific plans, strategies, results and achievements to external partners, internal stakeholders and senior management.
• Support new business opportunities by defining strategic DMPK requirements and contributing to proposals and client discussions.
• Interpret and integrate data across disciplines to guide project decisions, including the optimisation of ADME and PK properties, DDI assessments, formulation recommendations and PKPD or PBPK modelling.
• Ensure robust human PK and dose predictions throughout the project…