Senior Scientist - Metabolite Identification; AMS

Senior Scientist I - Metabolite Identification (AMS)

Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the UK, US, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services.

We are seeking a Senior Scientist I to join our AMS Metabolism team in Hoddesdon. This is an exciting opportunity for an experienced scientist with expertise in metabolite identification, high‑resolution mass spectrometry (HRMS), and LC‑MS/MS data interpretation to play a key role in supporting drug development programmes.

Working as a technical specialist within the group, you will lead metabolite identification activities for both regulatory and non‑regulatory studies, contribute to scientific discussions with clients, support the development of innovative analytical approaches, and help drive continuous improvement across the department.

• Act as a technical expert in metabolite identification and structure elucidation using High Resolution Mass Spectrometry.
• Conduct analytical and metabolite identification studies to meet project timelines and client requirements.
• Develop and optimise LC‑MS/MS chromatographic methods and provide scientific consultation across the wider Metabolism Department.
• Interpret complex analytical data and prepare accurate scientific updates, reports, and study documentation.
• Support client interactions, including scientific discussions, meetings, teleconferences, and site visits.
• Provide technical updates to Project Managers, Study Directors, and senior management throughout the study lifecycle.
• Ensure all work is performed and documented in accordance with GxP requirements, study plans, SOPs, and company standards.
• Maintain responsibility for assigned laboratory equipment, software platforms, and laboratory areas.
• Lead process improvement initiatives and support the development of new services and capabilities within the department.
• Contribute to the external scientific profile of the team through publications, presentations, posters, and participation in expert groups.
• Develop and deliver training materials while mentoring and supporting less experienced colleagues.
• Support project costing activities and provide technical input for bespoke client programmes.
• Participate in recruitment activities, including interviewing and assessing prospective candidates.

• PhD, MSc or BSc (Hons) in Chemistry, Biochemistry, or a related scientific discipline.
• Demonstrated experience in metabolite identification within a CRO, pharmaceutical, or agrochemical environment.
• Strong experience in chromatographic method development and optimisation.
• Experience working within regulated GxP environments.
• Proficient in the use of high‑resolution mass spectrometry platforms such as Waters Vion, Thermo Q Exactive, and Orbitrap systems.
• Experience using relevant software packages including Xcalibur, Waters UNIFI, and Compound Discoverer.
• Strong understanding of drug metabolism and metabolic pathways.
• Excellent LC‑MS/MS data interpretation and structure elucidation skills.
• Strong scientific reporting, presentation, and communication skills.
• Experience coaching, mentoring, and developing colleagues.
• Good project management, organisational, and problem‑solving abilities.
• Proficient with Microsoft Office applications.
• Ability to prioritise effectively and manage multiple projects in a fast‑paced environment.

• Salary Competitive
• Frequency Annual
• Job Reference ukpharmaron/TP/142/703
• Contract Type Permanent Contract
• Closing Date No expiry date
• Job Category Scientific (Metabolism (Met-))