Manager, Reliability

The Manager, Reliability develops, implements, and sustains the site reliability strategy, ensuring process, utility, and facility equipment achieves the availability and performance required for Good Manufacturing Practice (GMP) biologics manufacturing. The role leads the site programs for equipment criticality, reliability-centered maintenance (RCM), mechanical integrity, and condition-based maintenance (CBM),translating equipment risk into defensible, data-driven maintenance strategies. The Manager partners with Maintenance Operations, Process Engineering, Quality, and Validation to move the site from reactive and time-based maintenance toward proactive, condition- and risk-based practices.

Additionally, this role builds and leads a high-performing team of reliability engineers and CBM specialists while serving as thesite subject matter expert for reliability during audits and inspections

FUJIFILM Biotechnologies is building the future of bioproduction in Holly Springs, North Carolina. By end of 2025, we’ll open North America’s largest end-to-end CDMO biopharmaceutical manufacturing facility, offering drug substance production, fill-finish, and packaging under one roof.

We’re looking for passionate, mission-driven people to help us realize this exciting vision and deliver the next vaccine, cure, or therapy. We offer a dynamic work environment and we’re proud to cultivate a culture that will fuel your purpose, energy, and drive—what we call Genki. Ready to shape the future of medicine? Let’s transform healthcare together!

Holly Springs, North Carolina, combines small-town warmth with proximity to Raleigh’s thriving tech scene, making it the perfect blend of community and opportunity.

Fujifilm is globally headquartered in Tokyo with over 70,000 employees across four key business segments of healthcare, electronics, business innovation, and imaging. We are guided and united by our Group Purpose of “giving our world more smiles.” Visit:

What you'll do:

• Develops and owns the site reliability strategy and multi-year roadmap, aligning with the site maintenance master plan and ramp-up objectives while reporting progress and performance to maintenance and site leadership
• Leads and develops a high-performing team of engineers and specialists through servant leadership and reliability competencies while fostering a People First culture where members feel valued, respected, and supported
• Leads the equipment criticality assessment program, including the governing methodology and procedure, cross-functional assessment sessions, and maintenance of criticality rankings in the CMMS; partners with Process Engineering and Quality, who own process and product impact determinations, and ensures criticality drives maintenance strategy, work prioritization, and spare parts stocking
• Leads RCM and failure mode and effects analyses on critical assets to identify functional failures, failure modes, and consequences, and to select the most effective maintenance tasks, ensuring strategies are implemented in the CMMS and in controlled documents
• Establishes and scales the CBM program in phases, including technology selection (e.g., vibration analysis, infrared thermography,ultrasound, oil analysis, motor circuit analysis), route design, baseline and alarm limits, data trending, and integration of findings intothe work management process
• Develops and implements the mechanical integrity program for pressure vessels, piping systems, pressure relief devices, and other pressure-retaining and safety-critical equipment, including inspection and test plans, jurisdictional requirements, deficiency management, and records retention
• Partners with Maintenance Operations and Process…