Maintenance Engineer

Location
:
Houston, TX (Onsite)
Department
:
Equipment
Reports to
:
Manager, Equipment

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, located in the heart of the Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, and TCR-T. Our expert team collaborates closely with MD Anderson’s research and clinical faculty, bringing impactful cell therapies to cancer patients.

Since inception in May 2022, our team has filed eight INDs and have received approval, without delay, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.

Our growing, state‑of‑the‑art, 60,000 sq. ft. industrial facility in the Texas Medical Center is staffed by an integrated team of industry veterans and academic scientists who are passionate about bringing life‑saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long‑term horizon to achieve our organizational goals.

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure to inspire professional growth and satisfaction. We foster a team‑first culture and a balanced work‑life environment to ensure our staff is energized and engaged in our mission to accelerate cell therapies from bench to bedside for patients who need them. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application.

We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.

As an Equipment Engineer, you will provide technical oversight of all Cell Therapy and Viral Vector equipment and will work with the Manufacturing and Quality Control departments during the full equipment life cycle. This role supports day‑to‑day operations, equipment qualification, preventive maintenance, and troubleshooting across all critical GMP departments, including such equipment as incubators, Biological Safety Cabinets, Lovos, Prodigies, and any new Cell Therapy equipment.

• Establish and maintain preventive and predictive maintenance programs to maximize equipment uptime.
• Troubleshoot equipment issues, perform root‑cause analyses, and drive corrective actions.
• Collaborate with external service providers to ensure timely, compliant service activities.
• Update Maximo CMMS promptly upon completion of maintenance tasks.
• Author and execute IQ/OQ/PQ protocols in compliance with GMP and regulatory guidelines (FDA, ICH).
• Partner with Quality, Validation, and Manufacturing teams to ensure equipment qualification documentation is accurate and audit ready.
• Manage equipment change controls and support technical assessments for deviations and CAPAs, ensuring adherence to timelines.
• Train manufacturing and laboratory staff on proper equipment operation procedures, when required.
• Ensure that changes, maintenance and other interventions do not adversely impact the qualification state of the equipment.
• Lead/support the tech transfer of new equipment and unit operations across Equipment development and manufacturing
• Provide technical oversight during development of equipment and Equipment system User Requirements and related Design Review/Qualification documentation to ensure equipment and systems are appropriate for intended purpose.
• Provide guidance in development of test plans for Verification packages and associated critical components.
• Provide guidance on key elements of return to service requirements for equipment after interventions such as maintenance.
• Assist during internal and external audits, providing technical expertise and documentation as required.
• Assist and support…