Postdoctoral Fellow - Leukemia - Research

Postdoctoral Fellow – Leukemia – Research

A postdoctoral fellow position is available in the Section of Molecular Hematology & Therapy, Department of Leukemia at the University of Texas MD Anderson Cancer Center under the mentorship of Michael Andreeff, MD, Ph.D.

We are seeking a highly motivated and innovative individual with advanced clinical experience in hematologic malignancies and technical expertise in cell, molecular, or cancer biology to lead a project focused on developing new analytical modalities for identifying novel vulnerabilities and creating hypothesis‑driven, mechanism‑based molecular targeting strategies for drug‑resistant leukemias.

Conduct research on cell death and cell survival pathways, and mechanisms of drug resistance in myeloid leukemia stem cells through a combinatorial study using molecular biology methodologies. This includes gene editing, mutation detection, gene and protein expression analysis, chromatin accessibility profiling, and evaluation of responses to drug treatments in both in vitro and in vivo leukemia cell systems. The goal is to broaden understanding of cell death regulators, signaling pathways, and leukemia microenvironmental factors, clarify their roles in drug resistance, and develop a mechanism‑based approach to overcome therapeutic resistance.

• Collaborate within an interdisciplinary project involving cell culture, flow cytometry, mass cytometry, western blot analysis, immunohistochemistry, RT‑PCR, DNA/RNA sequencing, and patient‑derived xenograft leukemia and murine leukemia models using animals.
• Write scientific reports and present findings in project meetings, national and international conferences, and high‑impact scientific publications.

• Recently graduated physician‑scientist with an M.D. and/or Ph.D. degree, with expertise in cell, molecular, and cancer biology and strong knowledge of cell death pathways and cell signaling.
• Proficiency in laboratory techniques: cell culture, drug treatment, cell death assays, molecular cloning, flow cytometry, and/or experience with murine models of leukemia.
• Data analytic skills using innovative analytical approaches are highly desirable.
• Excellent written and spoken English communication skills, ability to provide both practical and theoretical training to students, foster scientific collaboration, and exhibit first‑author publications in high‑impact peer‑reviewed journals in hematology.

MD Anderson offers full‑time postdoc positions with a salary ranging from $64,000 to $76,000 depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.

Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements.

This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code, and may require routine reviews and screening. All requirements necessary to ensure the continued security and integrity of such infrastructure are a condition of hire and continued employment.

• Internship

• Full‑time

• Research, Analyst, and Information Technology
• Hospitals and Health Care (Industry)

The University of Texas MD Anderson Cancer Center provides equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://(Use the "Apply for this Job" box below)..html