Senior Bioinformatics Software Engineer: Data Pipelines & Analytics

Job Category: Information Technology (IT)

Requisition Number: SRBIO
002447

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• Posted :
  August 3, 2026
• Full-Time
• Hybrid

Showing 1 location

Houston, TX 77021, USA

JOB SUMMARY

The Senior Bioinformatics (BI)
Software Engineer holds acriticaltechnical role, responsible for designing, developing, andmaintainingscalable and efficientsoftwaresolutionsfor

Baylor

Genetics’bioinformaticpipelines. This role involves collaborating withand supporting cross-functional teams to deliver data-drivensoftwaresolutionsaligning with business needs.

KEY RESPONSIBILITIES

• BI Development:Design, develop, andmaintainrobustsoftwaresolutions using various tools, databases, and technologies to meet business requirements.
• Data Modeling:Create and optimize data models, ensuring the accuracy, integrity, and performance of theunderlingcomputational algorithms, especially as pertains to assembly, mapping,variantcallingand variant annotation.
• ETL Processes:Develop andoptimizeETL (Extract, Transform, Load) processes to efficiently extract data from various sources, transform it, and load it into the BI system, with an emphasis onutilizingAPIs
• Query Optimization:Analyze andoptimizeSQL queries and database performance to enhance data retrieval and reporting speed.
  
  Contribute to schema design and review sessions to ensure high performance and maintainable databases.
• Dashboard & Report Creation:Develop interactive dashboards andautomatedreports using BI tools (e.g.,Azure Pipelines, Teams Power Automate,email,Nextflow) to provide actionable insights for stakeholders.
• Collaboration:Workand align closely with stakeholders, including data analysts, business users,clinical reviewers, laboratorypersonneland software developers, toscope theirrequirementsand delivertimelyintegrationsof new software.
• Data Integration:Integrate disparate data sources and ensure consistency, accuracy, and reliability of data across the BI system, with a focus on devising systems that have minimal to no code debt and are highly maintainable and flexible.
• Quality Assurance:Conduct rigorous testing of BI solutions to ensure data accuracy, system stability, andoptimalperformance, with the ability to automatetestingsuites using packages(e.g.pytest,doctest,Azure Pipelines)
• Documentation & Maintenance:Create comprehensive documentation for developed solutions and provide support andmaintenanceas necessary.
  
  Thisgenerallyincludes: (1) detailed in-line commenting noting
  
  Jira ticket request numbers, genomic diagrams,reasoning and personal thoughts, TODO comments, docstrings, BG headers, etc.; (2) wikis and README files instructing users on how to install and implement the software along withtrace mappings detailing how the software is generally organized.

QUALIFICATIONS

Required

• Education:Bachelor’s degree in Computer Science, Software Engineering,Bioinformaticsora related field;
  
  Master’sdegree preferred.
• Experience:Minimum of 5 years of experience in software development, with a proven track recordof designing and implementing scalable software solutions based on diverse user feature needs. Must have a proven track recordof implementing production ready software solutions from scratch. Prior experience or domain knowledge from collaborating with laboratory scientists, computational biologists, or clinical reviewers is a nice-to-have.

COMPETENCIES

Technical Skills:

• Deep knowledge andexpertisein at least two programming languages (Python, Perl, R, or Bash, will also consider Java, C++, and Groovy).
• Proficient in a range of database technologies, including SQL Server, No
  
  SQL, MongoDB, MySQL, and Elastic
  
  Search,demonstrating comprehensive skills in database management, optimization, and query development.
• Proficiency in working in an Agile framework and implementing CI/CD practices…