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Clinical Nurse III

Job in Irvine, Orange County, California, 92713, USA
Listing for: City of Hope
Full Time position
Listed on 2026-01-04
Job specializations:
  • Nursing
    Healthcare Nursing, Clinical Nurse Specialist
Salary/Wage Range or Industry Benchmark: 61 - 89 USD Hourly USD 61.00 89.00 HOUR
Job Description & How to Apply Below
Position: Clinical Nurse III -  ETC, Days

Join to apply for the Clinical Nurse III – ETC, Days role at City of Hope
.

Base pay range: $61.00/hr – $89.00/hr

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life‑threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix.

Our dedicated and compassionate employees are driven by a common mission:
To deliver the cures of tomorrow to the people who need them today.

With the opening of the hospital, the full continuum of advanced cancer care—from prevention through survivorship—will be available in Orange County for the first time, eliminating the need to travel for lifesaving treatment. Seamlessly connected to our outpatient cancer center, the new clinical research hospital will feature 73 inpatient beds, advanced surgical suites, groundbreaking clinical trials, and holistic services such as rehabilitative therapy and spiritual care.

This isn’t standard cancer care. This is lifesaving cancer care. This is Hope.

We are seeking experienced nurses for our 8‑bed Evaluation and Treatment Center (ETC) at City of Hope Orange County Cancer Specialty Hospital
. As a Clinical Nurse III in the ETC you will provide compassionate care to our oncology patients who are requiring urgent evaluation and intervention. This role is vital in addressing acute symptoms related to cancer, treatment side effects, and oncologic emergencies.

The Clinical Nurse III performs rapid assessments, triage, and stabilization with strong understanding of oncology pathophysiology and the unique needs of immunocompromised patients. You will collaborate closely with physicians and the interdisciplinary care team, ensuring timely, individualized care that prioritizes both safety and the dignity of the patient.

The position requires clinical expertise, strong critical thinking, emotional resilience, and a deep commitment to supporting patients and families.

Key responsibilities
  • Utilize the nursing process and practice standards as a framework for the management of patient care.
  • Assess patient conditions, recognize early signs of complications, and initiate escalation of care when necessary, ensuring continuity of care through coordination with inpatient, outpatient, and palliative teams.
  • Administer specialized medications, monitor treatment responses, and manage central lines and infusion devices.
  • Demonstrate knowledge of the clinical information system and apply principles to patient documentation.
  • Prioritize holistic care, addressing both the physical and emotional needs of the patients.
  • Serve as a mentor and role model to new staff members.
  • Delegate to licensed and unlicensed personnel.
  • Integrate and practice according to the City of Hope Professional Practice Model to deliver care service excellence.
  • In alignment with City of Hope mission and values, the Division of Nursing and Patient Care Services vision, and with continuous focus on the patient, family and community, carry out the nursing process, coordinate interdisciplinary care planning, and document according to standards, ensuring the patient and caregiver’s understanding of the plan of care and expected outcomes.
  • Act as a change agent, committed to lifelong learning and professional development, embodying City of Hope organizational mission and values and the ethos of the nursing profession.
  • Shift: Days
  • Multiple positions available.
Qualifications
  • Bachelor’s Degree.
  • 3–5 years of related experience (urgent care, emergency room and/or ICU).
  • Current CA Registered Nurse License.
  • Current Basic Life Support (BLS) through American Heart Association.
  • Current Advanced Cardiac Life Support (ACLS) through American Heart Association.
  • ONS certification is highly preferred.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please .

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