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Senior Scientist I​/II, Drug Delivery Modeling & Simulation

Job in Irvine, Orange County, California, 92713, USA
Listing for: BioSpace
Full Time position
Listed on 2026-01-04
Job specializations:
  • Science
    Research Scientist, Data Scientist
Job Description & How to Apply Below
Position: Senior Scientist I / II, Drug Delivery Modeling & Simulation

Senior Scientist I / II, Drug Delivery Modeling & Simulation

Abb Vie’s mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, and products and services in our Allergan Aesthetics portfolio.

Job Description

As a Senior Scientist I or II in Abb Vie Drug Delivery Sciences, you will work as a key part of a talented, multidisciplinary, cross‑functional team to build cutting‑edge capabilities for the delivery of biologics and small molecules and advance new products through early R&D. We are seeking a highly motivated PhD Chemical Engineer specializing in the modeling and simulation of drug release kinetics in advanced drug delivery systems.

The successful candidate will apply first‑principles understanding to design, optimize, and analyze drug delivery platforms, utilizing quantitative models to predict and control drug release profiles.

Responsibilities
  • Develop and apply mechanistic models for drug release kinetics from various sustained drug delivery platforms (e.g., in situ forming depots, implants, hydrogels).
  • Employ first‑principles approaches (diffusion, convection, chemical reaction theories) to solve complex transport problems relevant to drug delivery formulations.
  • Design, execute, and analyze computational simulations using tools such as COMSOL Multiphysics or similar platforms.
  • Collaborate with formulation and material scientists and pharmacologists to translate modeling results into experimental design and product development.
  • Interpret experimental release data and integrate findings into enhanced models for predictive accuracy.
  • Communicate findings through technical reports, publications, and presentations.
Qualifications
  • PhD in Chemical Engineering.
  • For Senior Scientist I: 0–4 years of relevant experience (industry, post‑docs, or academia).
  • For Senior Scientist II: 4+ years of relevant industry experience.
  • Strong foundation in mass transport phenomena (diffusion, dissolution, convection, degradation).
  • Demonstrated expertise in mathematical modeling and simulation of controlled release mechanisms.
  • Proficiency in relevant modeling and simulation software (COMSOL Multiphysics, Monte Carlo methods, or equivalent).
  • Excellent problem‑solving, quantitative, and communication skills.
  • Ability to work collaboratively in a multidisciplinary environment.
  • Prior experience with drug delivery system design and evaluation is preferred.
Leadership Competencies
  • Comfortably deals with risk and ambiguity, changing course when needed.
  • Lives Abb Vie values: acts consistently with our ethics, obligations, and the law.
  • Acts respectfully yet courageously.
  • Communicates openly and honestly with all colleagues.
  • Looks outside Abb Vie for new ideas to stimulate innovation.
  • Connects unrelated concepts, generates original or unique ideas.
  • Persistent and resilient – finds the way to move good ideas forward.
Additional Information

Location:

On‑site at Abb Vie’s Irvine, CA location.

Compensation:
The range described below is the proposed base pay range that the Company believes in good faith it will pay for this role at the time of posting, based on the job grade. Individual compensation paid within this range will depend on many factors including geographic location and may be modified in the future.

Benefits:
We offer a comprehensive package including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) for eligible employees. This job is eligible for short‑term and long‑term incentive programs.

Note:

Any bonus, commission, incentive, benefits, or other form of compensation is at the Company’s sole discretion until earned and vested.

Abb Vie is an equal‑opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer / Veterans / Disabled. US & Puerto Rico applicants seeking reasonable accommodation may refer to the company’s policy.

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Position Requirements
10+ Years work experience
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