Principal Software Engineer, Product Engineering

Location:

This is a hybrid in-office role; NJ or NYMedidata follows a hybrid office policy in which employees who are hired for an in-person position are expected to work on site a certain number of days per week following Company policy.

About our Company:

Medidata is powering smarter treatments and healthier people through digital solutions to support clinical trials. Celebrating over 25 years of ground-breaking technological innovation across more than 38,000 trials and 12 million patients, Medidata offers industry-leading expertise, analytics-powered insights, and one of the largest clinical trial data sets in the industry. More than 1 million registered users across approximately 2,300 customers trust Medidata's seamless, end-to-end platform to improve patient experiences, accelerate clinical breakthroughs, and bring therapies to market faster.

A Dassault Systèmes brand (Euronext Paris: FR0014003TT8, DSY.PA), Medidata is headquartered in New York City and has been recognized as a Leader by Everest Group and IDC. Discover more at . Listen to our latest podcast, from Dreamers to Disruptors, and follow us at ut the Team:

Medidata's Product Organization is staffed with a passionate team of product management experts, tackling the industry's most difficult technical challenges in order to push the boundaries of possibility for our clients and most importantly, for patients. Together we can deliver meaningful advanced digital transformation to the industry in order to achieve our vision.

Medidata is seeking an experienced Principal Software Engineer to develop the next generation of Medidata's software applications. While working in a collaborative, cross-functional team environment, you will have the autonomy to build solutions that resolve complex problems and bring to market enterprise grade products offering consumer class experience and design. This role will report to VP, Engineering.

Responsibilities Direct the long-term technical evolution and architectural strategy for the Study Experience, ensuring tight alignment with core product objectives and business initiatives.

Architect and deploy sophisticated distributed environments designed for high availability, robust security, and cost-efficiency under heavy operational loads.

Orchestrate engineering efforts across multiple domains by clarifying ambiguous requirements, finalizing technical compromises, and enabling seamless cross-team integration.

Establish the foundational engineering benchmarks and shared infrastructure patterns—including libraries and frameworks—that optimize developer velocity.

Manage architectural oversight by facilitating design consultations, documenting RFCs and ADRs, and serving as the final authority on critical technical choices.

Drive innovation through research and rapid prototyping of emerging capabilities—such as AI/ML and edge computing—and transition successful experiments into production.

Consult with senior executives and product leadership to translate high-level goals into technical roadmaps while maintaining transparency regarding risks and investment costs.

Cultivate the growth of Senior and Staff-level engineers, elevating the organization's collective expertise in design philosophy and operational trade-offs.

Champion operational excellence by implementing SLOs, observability standards, and incident response protocols while optimizing cloud expenditure.

Position Requirements Extensive background in distributed systems, encompassing consistency models, fault-tolerant design, and event-driven architectures for high-throughput environments.

Proven success in delivering large-scale production systems—characterized by multi-region deployments or massive data volumes—that drive business impact.

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