Postdoctoral Research Fellow- UFMylation, Tau Biology & Neurodegeneration

The Fiesel Laboratory in the Department of Neuroscience at Mayo Clinic in Jacksonville, Florida, is seeking highly motivated postdoctoral research fellows to investigate molecular and cellular mechanisms underlying neurodegenerative diseases.

Current projects focus on protein homeostasis and UFMylation in tauopathies, mechanisms of tau aggregation and propagation, and mitochondrial quality control pathways relevant to Parkinson’s disease. Projects use complementary approaches including molecular and cellular biology, biochemistry, human iPSC‑derived neuronal models, advanced imaging, proteomics, and in vivo disease models.

The successful candidate will have the opportunity to develop an independent research direction within these funded programs and work in a highly collaborative neuroscience environment.

Ph.D. or equivalent doctoral degree in neuroscience, cell or molecular biology, biochemistry, biomedical sciences, or a related discipline.

Candidates should have a strong research background and demonstrated experience in one or more of the following areas: neurodegeneration, protein homeostasis/proteostasis, tau or other protein aggregation disorders, mitochondrial biology, molecular and cellular neuroscience, iPSC‑derived neuronal models, proteomics, advanced imaging, or in vivo disease models.

Strong scientific communication skills, a record of research productivity, and the ability to work both independently and collaboratively are expected.