Assistant Professor - CanBio

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** Job Description

Summary:

** The Department of Cancer Biology at the University of Kansas Medical Center seeks an Assistant Professor to establish an innovative and collaborative research program at the interface of cancer biology, extracellular vesicle biology, liquid biopsy, precision medicine, and therapeutic delivery. The successful candidate will develop an independent research program focused on understanding and exploiting tumor-derived cells, extracellular vesicles, nucleic acids, and other circulating biomarkers to advance cancer detection, disease monitoring, therapeutic stratification, and novel treatment approaches.
The position is particularly suited for a scientist with interdisciplinary expertise spanning cancer biology, bioanalytical chemistry, bioengineering, extracellular vesicles, microfluidics, and molecular diagnostics. The faculty member will be expected to integrate fundamental cancer biology with enabling technologies for the isolation, characterization, and functional analysis of rare cells and extracellular vesicles from complex biological samples. Particular emphasis will be placed on translating these technologies into clinically relevant approaches for precision oncology.
An important component of the research program will be the development of extracellular vesicles as both biomarkers and functional biological systems. Research may include characterization of extracellular-vesicle cargo, investigation of EV-mediated cellular communication, development of EV-based molecular signatures, and engineering of extracellular vesicles or related nanoscale systems for targeted therapeutic delivery. The candidate's existing research portfolio includes EV mRNA profiling, EV isolation and analysis, and a current project investigating extracellular vesicles for drug delivery, providing a strong foundation for development of this area as an independent research direction.
The successful candidate will also develop and apply liquid-biopsy technologies for translational cancer research, including circulating tumor cells, extracellular vesicles, cell-free nucleic acids, and other disease-associated biomarkers. These approaches may be applied to questions such as tumor heterogeneity, minimal residual disease, treatment response, mechanisms of metastasis, and emergence of therapeutic resistance. The candidate has demonstrated experience applying these approaches across multiple cancer types, including pancreatic, colorectal, ovarian, breast, hematologic, and head and neck malignancies.##

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* Job Description:

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* Key Roles and Responsibilities:

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* * Establish and maintain an independent, externally funded research program in cancer biology with emphasis on extracellular vesicles, liquid biopsy, precision oncology, and/or therapeutic delivery.
* Develop innovative technologies and functional assays for isolation, characterization, and molecular analysis of extracellular vesicles, circulating tumor cells, nucleic acids, and other cancer-associated biomarkers.·
* Investigate the biological roles of extracellular vesicles and circulating tumor-derived materials in tumor progression, metastasis, treatment response, and resistance.·
* Develop EV-based or complementary nanoscale approaches for targeted drug and nucleic-acid delivery, creating opportunities for collaboration with investigators in cancer therapeutics, drug delivery, and experimental therapeutics.·
* Translate bioanalytical and microfluidic technologies into robust tools for preclinical and clinical cancer research.·
* Pursue independent and collaborative extramural funding from the NIH, NCI, foundations, and other appropriate agencies.·
* Publish research findings in peer-reviewed journals and present results at national…