Research Associate II

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Compensation

$70,000 - $85,000 per year. Eligible for a Short‑Term Incentive Plan with a target of 5% of annual earnings; terms and conditions apply.

The Research Associate II is responsible for supporting the design, development and execution of novel assays based on Next‑Generation Sequencing and Long Read Sequencing. This role supports Ambry’s translational research initiatives, including internal and external collaborations, working under minimal supervision. The position works as part of a multidisciplinary team including R&D scientists, bioinformatics scientists, project managers and clinical laboratory personnel.

• Perform DNA/RNA isolation from biospecimens such as blood, saliva and buccal swabs.
• Library preparation for long/short read sequencing; monitoring sequencing metrics.
• Track project progress and maintain an up‑to‑date electronic laboratory notebook.
• Conduct data analyses and present findings during internal and external meetings.
• Draft work instructions, standard operating procedures and other supporting documentation.
• Contribute to the design and development of novel assays for translational research projects and support their transition to the clinical setting.
• Other duties as assigned.

• BS or MS degree in a life sciences field:
  Biology, Molecular Biology, Biochemistry, or related field.
• Strong understanding of molecular biology and genetics.
• Experience with DNA/RNA extraction from biospecimens such as whole blood, saliva and buccal swabs.
• Experience with library preparation for short or long read sequencing and subsequent analysis and interpretation of sequencing metrics.
• Experience with molecular biology techniques such as PCR and gel electrophoresis.
• Good command of Word, Excel and PowerPoint, or equivalent office programs.

• BS with 3+ years or MS with 1+ year of laboratory research experience in an academic or industrial setting.
• Strong understanding and previous experience working on human genetics.
• Proficiency in library preparation for short or long read sequencing, DNA/RNA extraction from biospecimens (blood/saliva/buccal), PCRs and analysis of electrophoretic traces.
• Excellent verbal and written communication skills and ability to work effectively as part of a multidisciplinary team.
• Ability to present organized summaries to internal or external stakeholders.
• Excellent organizational and record‑keeping skills.
• Strong willingness to learn new laboratory techniques and procedures, and expand knowledge about genetic variation and its connection to genetic diseases.
• Interest in learning more about data interpretation.
• Good command of sequencing metrics interpretation.
• Previous hands‑on experience with long‑read sequencing will be positively valued.

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