Scientist, Downstream Vaccines and Advanced Biotechnologies; VAX) Process R&D

** Job Description
**** Role

Description:

** We are seeking an innovative, highly motivated, and experienced Scientist to join us at our research and development site in West Point, PA. The candidate will be responsible for scientific/technical contributions and leadership of bioconjugation process development, and will also be a critical member of cross-functional program/project teams.

This role will require frequent collaboration with cross-functional teams including Analytical, Formulation, Process Chemistry, Enabling Technologies, and Manufacturing colleagues. The candidate should have a strong background in downstream bioprocess/bioconjugation design, including reaction steps, filtration (tangential and normal flow) and column chromatography.
*
* Primary responsibilities:

*** Independent design, execute, and analyze process development experiments to maximize vaccine production processes, thereby de-risking later stage development and tech transfer.
* Leadership roles in downstream process design and development for vaccine candidates.
* Represent functional area in cross-functional and strategic teams engaged in vaccine development.
* Lead tech transfer of vaccine drug substance processes for clinical and commercial manufacture.
* Serve as a scientific/technical mentor. Provide technical guidance in the various aspects of downstream bioprocess/bioconjugation development.
* Support strategic initiatives and innovation in the areas of vaccine and advanced biotechnology process development.
* Analysis of experiments through analytical techniques including HPLC, electrophoresis, light scattering, and spectroscopy.
* Data interpretation and presentation, manuscript/patent preparation.
** Education Minimum Requirement:
*** BS, MS or PhD in engineering or bio/chemical sciences:
* Chemical Engineering, Bioengineering, Biomedical Engineering, Chemistry, Biochemistry, Molecular Biology, Biotechnology
* For BS candidates, at least two (2) years of experience in a pharmaceutical or biotechnology-related position
* For MS candidates, at least one (1) year of post-graduate experience in bioprocess/biotechnology-related position (vaccines and/or therapeutic proteins) or relevant academic research thesis.
** Required

Experience and Skills:

*
* * Must have scientific understanding of downstream bioprocess purification processes.
* Scientific understanding of purification operations of large complex molecules.
* Technical understanding of bioprocess scaling principles.
* Prior hands-on bioprocess development experience through academic lab or industry experience.
* Position requires employee to be willing to work with infectious agents and/or pathogens.
* Position requires occasional travel and off hour/weekend work.
* Strong scientific and hands-on understanding of downstream bioprocess/bioconjugation unit operations, biotherapeutic and/or vaccine process development and sound understanding of scale-up principles.
* Ability to work effectively both independently and in a team-focused environment.  
** Preferred

Experience and Skills:

*** Prior hands on experience with any of the following purification bioprocesses:
Tangential Flow Filtration, Dead-End Filtration, Chromatography, or Homogenization.
* Experience in Process Tech Transfer to production facilities.
* Experience with biomolecule conjugation (e.g., conjugate vaccines, antibody-drug conjugates), conjugation chemistry and downstream bioconjugate processing.
* Strong understanding of, or hands-on experience in, cGMP manufacturing.  
*
* Required Skills:

** Analytical Biochemistry, Analytical Biochemistry, Analytical Chemistry, Antibody Drug Conjugates (ADC), Biochemistry, Bioconjugation, Biological Engineering, Biologics, Bioprocess Engineering, Bioproduction, Biotechnology, Chemical Engineering, Data Analysis, Downstream Processing, Drug Development, Laboratory Analytical Techniques, Materials Science, Messenger RNA, Molecular Biology, Molecular Cloning, Pharmaceutical Sciences, Process Scale Up, Product Development, Product Formulation, Protein Purifications {+ 1 more}
** Preferred

Skills:

** Current Employees apply HERE Current Contingent Workers apply HERE
** US and Puerto Rico Residents Only:
** Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please  if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and…