Senior Research Scientist - Medicinal Chemistry

About the Role

Our client is seeking a highly motivated and experienced Senior Research Scientist in Medicinal Chemistry to contribute to their drug discovery efforts in Kimberley . This role is essential for designing, synthesizing, and optimizing novel small molecule drug candidates. You will work collaboratively within a multidisciplinary team, applying cutting-edge synthetic techniques and medicinal chemistry principles to identify and develop compounds with therapeutic potential.

The ideal candidate is passionate about innovation in drug discovery and eager to make a significant impact on the development of new medicines, supported by excellent research facilities and a collaborative scientific community.

• Design and synthesize novel small molecules with desirable pharmacological profiles.
• Optimize lead compounds through iterative cycles of design, synthesis, and testing.
• Apply structure-activity relationship (SAR) principles to guide compound optimization.
• Collaborate closely with biologists and pharmacologists to evaluate compound efficacy and safety.
• Troubleshoot synthetic challenges and develop efficient synthetic routes.
• Author scientific reports, contribute to patent applications, and present findings at internal meetings.

• Ph.D. in Medicinal Chemistry, Organic Chemistry, or a closely related field.
• Minimum of 5 years of post-doctoral or industry experience in medicinal chemistry and drug discovery.
• Strong proficiency in synthetic organic chemistry techniques and analytical characterization methods (NMR, MS, HPLC).
• Demonstrated experience in drug discovery projects and understanding of SAR.
• Knowledge of computational chemistry tools and their application in drug design is beneficial.
• Excellent problem-solving skills and ability to work effectively in a team-oriented environment.

• Competitive salary and a comprehensive benefits package including health and retirement plans.
• Performance-based bonuses tied to project milestones.
• Support for professional development, including attendance at scientific conferences.
• A stimulating and collaborative research environment in Kimberley .
• Opportunity to work on impactful drug discovery programs and contribute to new therapies.