Senior Research Scientist - Medicinal Chemistry

About the Role  Our client is seeking a highly motivated and experienced Senior Research Scientist in Medicinal Chemistry to contribute to their drug discovery efforts in Kimberley . This role is essential for designing, synthesizing, and optimizing novel small molecule drug candidates. You will work collaboratively within a multidisciplinary team, applying cutting-edge synthetic techniques and medicinal chemistry principles to identify and develop compounds with therapeutic potential.

The ideal candidate is passionate about innovation in drug discovery and eager to make a significant impact on the development of new medicines, supported by excellent research facilities and a collaborative scientific community.

Key Responsibilities   Design and synthesize novel small molecules with desirable pharmacological profiles.
Optimize lead compounds through iterative cycles of design, synthesis, and testing.
Apply structure-activity relationship (SAR) principles to guide compound optimization.
Collaborate closely with biologists and pharmacologists to evaluate compound efficacy and safety.
Troubleshoot synthetic challenges and develop efficient synthetic routes.
Author scientific reports, contribute to patent applications, and present findings at internal meetings.
Requirements   Ph.D. in Medicinal Chemistry, Organic Chemistry, or a closely related field.
Minimum of 5 years of post-doctoral or industry experience in medicinal chemistry and drug discovery.
Strong proficiency in synthetic organic chemistry techniques and analytical characterization methods (NMR, MS, HPLC).
Demonstrated experience in drug discovery projects and understanding of SAR.
Knowledge of computational chemistry tools and their application in drug design is beneficial.
Excellent problem-solving skills and ability to work effectively in a team-oriented environment.
Benefits   Competitive salary and a comprehensive benefits package including health and retirement plans.
Performance-based bonuses tied to project milestones.
Support for professional development, including attendance at scientific conferences.
A stimulating and collaborative research environment in Kimberley .
Opportunity to work on impactful drug discovery programs and contribute to new therapies.

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