Sr. Manager, Chargeback and Pricing Operations

This role sits at the intersection of Pricing & Commercial Operations and Finance, providing commercial insights and analytics to support Gross-to-Net ("GTN") management across Pfizer’s U.S. Hospital Injectable and Biosimilar portfolio, with a primary focus on pricing, contracting and chargebacks. You will analyze contracting terms, pricing dynamics, and chargeback trends to assess and communicate their impact on GTN, revenue, margin, and overall profitability.

In this high-impact role, you will develop and analyze chargeback, rebate, admin fees, and other key GTN assumptions, identify business drivers and trends, and translate complex price-related contracting activity into clear, actionable insights for stakeholders across Commercial and Finance. You will support forecasting and planning and help strengthen understanding of how commercial decisions translate into financial performance. The role will also help advance automation and AI-enabled analytics to improve the speed, transparency, and quality of GTN analysis, forecasting, and decision-making.

Provide analytics to inform GTN assumptions, with a primary focus on contracting and chargebacks, and advise stakeholders on the impact of 340B, Medicaid, and other key GTN drivers on revenue and profitability. Support chargeback accrual pipeline calculations and related analytics using Finance- and Controllership-approved methodologies and assumptions. Analyze contracting activity, claims, utilization, pricing trends, and other commercial data to identify emerging trends and assess potential impacts to GTN and revenue forecasts.

Compare commercial assumptions with actual experience, identify key drivers of variance, and provide business rationale and analytics to support forecast refinement and decision-making. Partner with Finance, Controllership, and Commercial stakeholders to provide the data, insights, and business context needed to support GTN forecasting, accrual assessment, reconciliation, and financial reporting.

Partner with Finance to inform GTN forecasts by providing commercial assumptions, analytics, and insights related to contracting, chargebacks, payer/channel mix, pricing actions, and new product launches. Provide commercial GTN inputs and business rationale to support Finance forecasting and planning cycles, including budget, latest estimates, reforecasts, and long-range planning. Model the GTN, revenue, and profitability impact of contracting strategies, including bids, committed contracts, off-cycle price actions, channel strategies, and business development initiatives, to inform decisions before they are finalized.

Develop what-if scenarios and key-driver sensitivities to assess the potential impact of contracting changes, market dynamics, and legislative changes, translating results into clear, actionable insights for Commercial and Finance stakeholders.

Serve as functional owner of the commercial revenue and demand data repository, ensuring its architecture accurately supports both GTN calculations and forecasting outputs. Ensure data integrity between the contract management system (Flex) and the corporate ERP; optimize use of chargeback and script-level data and third-party aggregators to improve rebate validation and forecast accuracy. Drive automation, scalable dashboards, and reporting improvements — leveraging AI-enabled tools responsibly, with appropriate governance and human oversight, to shift capacity toward insight generation.

Serve as a key liaison between PCO and Finance, translating commercial strategies and…