Process Engineer – Lilly Medicine Foundry

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first.

We’re looking for people who are determined to make life better for people around the world.

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first‑ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

Lilly is currently constructing an advanced research facility for production of API molecules for clinical trials located in Lebanon, IN. This facility is Lilly’s largest investment in a clinical trial manufacturing capacity and is intended to provide APIs for current and future products, including new modalities. This is a unique opportunity to be a part of the startup team for a greenfield manufacturing site, and the successful candidate will help to build the processes and facility to enable a successful startup into GMP manufacturing operations.

We are seeking a Process Engineer to support the pilot plant facility in Lebanon with a focus on peptide and oligonucleotide synthesis. This position involves solving technical challenges with equipment design, developing and sustaining process knowledge, optimizing processes, and managing equipment capabilities.

The Process Engineer provides technical assessment and support for production operations in the areas of developing and sustaining process knowledge, process and equipment support, process optimization, equipment capability and asset management, and engineering business systems. This role is to serve as a process engineer supporting drug substance active pharmaceutical ingredient (API) manufacturing for peptide and oligonucleotide synthesis. Perform impact and risk assessments for the peptide and oligo synthesizers and unit operations.

Learn the lab and plant design for the reactors including automation recipes and procedures. Ensure that people and their environment are safe and that company policies concerning safety are followed. Ensure processing equipment remains compliant with internal Quality System requirements, applicable engineering standards, and cGMP requirements. Assess rig fit by receiving the technical data package for new processes and performing modeling, simulations and/or experimental work as required to ensure heat and mass transfer are acceptable when scaling to the plant.

Active engagement and communication with HSE, Quality Assurance, Tech Services, Development, Operations, FUME/C&Q, Automation, Maintenance, Environmental Monitoring, and Manufacturing. Author, review, or approve high‑quality technical reports and regulatory submissions dealing with the work performed by the department. Ensure that records and technical notebooks are adequately maintained. Demonstrate engagement and employ a quality mindset in all endeavors by proactively identifying quality issues and communicating appropriately.

Develop or review plans and timetables for project work.

BS or MS in chemical engineering or related discipline and a minimum…