Principal Service Designer; office locations

Genomics England is a global leader in enabling genomic medicine and research, focused on creating a world where everyone benefits from genomic healthcare. Building on the 100,000 Genomes Project, we support the NHS’s world-first national whole genome sequencing service and run the growing National Genomic Research Library, alongside delivering numerous major genomics initiatives. By connecting research and clinical care at national scale, we enable immediate healthcare benefits and advances for the future.

Our mission is to provide the evidence and digital systems so that by 2035 genomics could play a role in up to half of all healthcare interactions, whilst securing the UK’s position as the best place to discover, prove and benefit from genomic innovations.

We are accelerating our impact and working with patients, doctors, scientists, government and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.

Behind the Healthcare and Research outcomes, Genomics England delivers through designing, developing and operating complex healthcare software systems.

We’re on the cusp of big changes with the real prospect of genomics becoming the fabric of everyday healthcare through the lifetime – from birth to old age.

We are seeking a Principal Service Designer to join Genomics England in supporting the delivery of our Adult Population Genomics Programme (APGP), an exciting initiative that will sequence the genomes of 150,000 adults to explore how we can support preventative healthcare, improve early disease detection, and enable personalised interventions.

In this role, you will define the service and operating model end-to-end, starting with establishing discovery priorities, designing how the service should operate, and identifying which components and assumptions need testing to inform the study design.

• Lead the design of our Adult Population Genomics Programme from strategy through to delivery, ensuring the service is user‑centred, cohesive, and impactful.
• Set and shape service strategy in partnership with Service Owner and senior leaders, defining vision, outcomes, scope, and long‑term direction.
• Navigate ambiguity and complexity to prioritise effectively and guide multidisciplinary teams toward impactful, outcome‑focused solutions.
• Oversee service design delivery across multiple work streams in the service, ensuring coherence, quality, and alignment to organisational strategy.
• Collaborate with product and delivery teams, facilitating co‑creation and decision‑making across internal and external stakeholders, while ensuring regulatory compliance and cohesive end‑to‑end service experiences.
• Collaborate with data, technology, and architecture teams in complex integration environments to ensure services are feasible, scalable, and future‑ready.
• Recommend, advocate for, and actively participate in design research to inform evidence‑based decision making.
• Scope your own work and support other designers in defining priorities and planning effectively across the service area.
• Coach and mentor fellow designers, helping them grow their skills and tackle complex service challenges with confidence.

• Demonstrated experience delivering human‑centred design in healthcare, life sciences or other highly regulated, complex environments, with a track record of impact and confidence navigating ambiguity and complex systems.
• Strong skills in facilitation, systems thinking, prioritisation, and strategic communication, enabling you to operate effectively in evolving contexts.
• Proven expertise in stakeholder engagement and influence, building trusted relationships with senior leaders, service owners, and multidisciplinary teams.
• Experience at Principal Design Lead or Principal Service Designer level, shaping service strategy, vision, and organisational direction, ideally within complex data or technical infrastructure environments.
• A portfolio showing end‑to‑end ownership of complex services, with breadth, scale of impact, and strategic…