Supervisor, Manufacturing, Cell Therapy

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high‑achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb Netherlands operates in Utrecht, The Netherlands, and is building a state‑of‑the‑art European Cell Therapy facility located at the Leiden Bio Science Park. The company is looking to grow its team in this exciting environment.

The Manager II, Manufacturing, Cell Therapy is responsible for leading a team that executes cell therapy manufacturing processes. Team scope is organized around Cell Therapy manufacturing unit operations such as media, selection, activation, or harvest, all of which are executed in accordance with Current Good Manufacturing Practices (cGMP’s) in both a clinical and commercial setting. The Manufacturing Operations Manager II is responsible for managing all aspects of the manufacturing unit operation team including, but not limited to, written procedures, patient and intermediate materials, equipment, and environment of the production area, while also serving as an example within their peer group.

• Manage the creation, implementation and compliance for all documentation, procedures and policies related to Cell Therapy operations.
• Head of Emergency Response team.
• Oversee operations within the requirements of a validated manufacturing system(s).
• Plan, assign and oversee daily operational activities associated with assigned areas of responsibility.
• Maintain operating and storage areas to ensure that they are compliant, efficient, effective and safe.
• Initiate change controls, notice of events, deviations and investigations.
• Identify strategic and operational issues to prevent deviations and maintain a compliant environment. Lead and manage the development of corrective and preventative actions, deviation responses and investigations.
• Manage implementation and maintenance of appropriate training curricula.
• Drive right‑first‑time initiatives and hold team accountable for compliance performance.
• Create an environment of teamwork, open communication, and a sense of urgency. Foster a culture of safety and compliance that embraces safety in the work environment and the safety of the patients by compliance with company procedures and policies, and cGMP requirements.
• Efficiently coordinate, communicate, and provide Operations project information and activities status to all stakeholders in a timely manner and in accordance with schedules and define implementation timelines.
• Presence in the cell therapy manufacturing facility to participate in walk‑throughs, provide process troubleshooting.

Preferred Experience:

7+ years of experience in cGMP cell therapy manufacturing, bioprocessing manufacturing, or relevant experience. Must have minimum of 3+ years leading a team.

• Cell therapy manufacturing.
• Aseptic processing in ISO 5 biosafety cabinets and universal precautions for handling human derived materials in BSL‑2 / ML‑1 containment areas.
• Cell expansion using incubators and single‑use bioreactors, cell washing processes, cell separation techniques and cryopreservation processes and equipment.

• Must be able to stand/walk for extended periods of time.
• Must be able to work in a cleanroom environment and perform aseptic processing in ISO 5 biosafety cabinets (as needed), which require gowning and personal protective equipment (PPE) such as safety shoes, safety glasses, aprons, face shields, powered air purifying respirators (PAPR), lab coats, full‑body gowns, hairnets, gloves and hearing protection.
• Required to carry and/or lift up to 30 pounds (15 kg), several times a day, while handling production equipment and/or materials.
• Required to push…