Senior Executive Assistant, Office CEO

Agenus is seeking an exceptional Senior Executive Assistant to join the Office of the CEO and work closely with the Chairman/Chief Executive Officer.

This is far more than a traditional executive assistant role. As part of a small, high-performing team, you will gain firsthand exposure to the leadership and operations of a Nasdaq-listed biotechnology company. You will work in the Office of the CEO and interact with senior executives, Board members, investors, business partners, and other key stakeholders.

You will be trusted with significant responsibility, encouraged to take ownership, and given the opportunity to expand your skills and progressively assume greater responsibilities. This position reports to the Director of Operations of the Office of the CEO, who will provide training and mentorship, with both roles working closely together to provide coverage and support.

This is an ideal opportunity for an experienced executive assistant who wants to expand beyond traditional administrative responsibilities and continue to build a career in executive operations and corporate leadership.

• Manage a complex, high-volume executive calendar across multiple time zones.
• Coordinate domestic and international travel, itineraries, and real-time changes.
• Serve as a trusted point of contact for internal and external requests.
• Manage communications, correspondence, follow-up, and action items.
• Anticipate needs, identify potential issues, and proactively resolve them.

• Provide discreet administrative support for select personal commitments and appointments.
• Handle sensitive business and personal information with exceptional judgment and confidentiality.

• Support the day-to-day operations and priorities of the Office of the CEO.
• Manage expenses, memberships, subscriptions, renewals, and other administrative responsibilities.
• Support the CEO's involvement with affiliated companies, philanthropic organizations, and other initiatives.
• Provide coverage for the Director, Operations, during absences.
• Identify opportunities to improve processes, increase efficiency, and leverage technology and AI.

• Coordinate Board meetings, leadership meetings, investor meetings, partner meetings, and executive visits.
• Manage travel, accommodations, agendas, presentations, briefing materials, and meeting logistics.
• Coordinate executive dinners, events, and high-profile engagements.
• Build professional relationships with Board Members, investors, executives, and external partners.

• 5+ years of executive support experience, supporting a C-suite executive.
• Experience in a public company, biotechnology, pharmaceutical, life sciences, financial services, or similarly fast-paced environment preferred.
• Exceptional organizational skills and attention to detail.
• Proven ability to manage complex calendars, international travel, and high-level meetings.
• Excellent written and verbal communication skills.
• Confidence interacting with senior executives, Board Members, investors, and external stakeholders.
• Exceptional judgment, discretion, and ability to prioritize independently.
• Highly proactive, resourceful, adaptable, and remain calm under pressure.
• Strong Microsoft 365 skills; ability to quickly learn new systems and technologies.
• Comfortable using AI tools such as Microsoft Copilot, ChatGPT, or Claude to improve productivity and executive support.
• Bachelor's degree preferred.
• Curiosity and enthusiasm for learning how a high-level executive office and public company operate.

• Onsite at the Lexington, MA headquarters, Monday through Friday. Core hours are 8:00 AM to 5:00 PM.
• The CEO hosts dinners and events regularly, typically 5:00 to 7:00 PM; the Senior Executive Assistant is expected to be available for these. Occasional weekend work for travel changes and time-sensitive matters.
• Occasional travel to the company's New York office.
• The office is dog-friendly; a dog is present regularly.

This position offers an unusual opportunity to learn from senior leadership, become an essential member of the Office of the CEO, broaden your professional skill set, and build a career at the highest levels of the organization.

You will have the opportunity to:

• Work directly with the Chairman and CEO of a Nasdaq-listed biotechnology company.
• Gain exposure to Board relations, corporate strategy,…