Manager​/Sr. Manager of Accounting

Valo Health is a human‑centric, AI‑enabled biotechnology company working to make new drugs for patients faster. The company’s Opal Computational Platform transforms drug discovery and development through a unique combination of real‑world data, AI, human translational models and predictive chemistry.

Our talented team of biologists, chemists and engineers, armed with advanced AI/ML tools, work together to break down traditional R&D silos and accelerate the speed and scale of drug discovery and development.

Valo is committed to hiring diverse talent, prioritizing growth and development, fostering an inclusive environment, and creating opportunities to bring together a group of different experiences, backgrounds, and voices to work together. We embrace new ways of learning, solve complex problems and welcome diverse perspectives that can help us advance patient‑centric innovation.

Valo is headquartered in Lexington, MA, with additional offices in New York, NY and Tel Aviv, Israel. To learn more, visit

Reporting to the Controller, the Assistant Controller will lead monthly, quarterly and annual close processes and ensure the accuracy, timeliness and integrity of financial data. The candidate will have a strong technical knowledge of U.S. GAAP and demonstrated success scaling accounting operations and improving processes within a fast‑paced, evolving organization.

The candidate will join a Finance team that values integrity, inclusiveness, executing for results, success as a team, and strong customer service. This is a hybrid role reporting to our Lexington, MA office, and the candidate is expected to be on site at least 3 days per week.

• Lead monthly, quarterly, and annual close activities, ensuring timely, accurate, and complete financial records and reporting in accordance with US GAAP, legal requirements, and Company policies.
• Prepare and review monthly journal entries, account analyses, balance sheet reconciliations, financial statements, and supporting reports with a focus on precision and data integrity.
• Demonstrated ability to manage revenue recognition for collaboration and milestone arrangements in accordance with U.S GAAP.
• Collaborate with Finance team members to prepare internal management reporting packages and various ad‑hoc analyses that support strategic decision‑making.
• Analyze and provide commentary on balance sheet and income statement variances, highlighting key drivers and trends.
• Manage corporate consolidations, including oversight of subsidiary reporting requirements and elimination entries.
• Oversee fixed asset accounting, including maintenance of the fixed asset subledger, application of capitalization policies, calculation of monthly depreciation, and preparation of related close schedules.
• Ensure proper documentation and control over accounting records, maintaining support required for legal, regulatory, and audit compliance.
• Support quarterly reviews and annual financial statement audits and assist with other ad hoc projects as directed by the Controller.
• Prepare annual regulatory reports and filings, such as property tax and other required submissions.
• Identify emerging business, operational, or technical risks and incorporate relevant updates into SOX compliance program documentation in a timely manner.
• Lead the preparation of the annual SOX risk assessment, including determining materiality thresholds, identifying in‑scope processes, and mapping significant accounts to key assertions and controls.
• Interface with external auditors for annual audits, quarterly reviews, and internal control testing, ensuring timely delivery of required schedules and documentation.
• Participate in special projects and ad‑hoc financial analyses in support of finance department priorities and broader company initiatives.

• Bachelor’s degree in accounting or related field; CPA required.
• Minimum of 7+ years of progressive accounting experience, with 3+ years of Big Four public accounting.
• Life sciences or biotech industry experience strongly preferred.
• Experience with Valo’s finance systems a plus, including Net Suite, Flo Qast, Prendio, and Adaptive Insights.
• Strong…