Applications Manager

Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown, Cambridge and Plainsboro reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas.

We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.

The Applications Manager will ensure reliable, compliant and efficient lifecycle management of business‑critical applications supporting facilities, building systems and enterprise operations within US R&D Operations, with primary responsibility for CMMS (Blue Mountain) and document systems. Lead application support, enhancements, user enablement and team performance to maintain operational continuity and improve system effectiveness. Align application capabilities and support services with business needs in close partnership with IT and operational stakeholders.

Reports to the respective leader of US Core Facilities and Engineering Services and provides leadership to applications technicians and other assigned support resources. Partners with the Facilities Associate Director on application strategy, operational priorities, enhancement planning and resource needs. Collaborates with Facilities, IT, Finance, Procurement, Quality, EH&S and other business stakeholders on application operations, user support, enhancements and compliance needs. Works closely with the IT Department to plan and coordinate implementations, upgrades, updates and ongoing support.

External relationships include software vendors, service providers and implementation partners supporting issue resolution, system changes and service delivery.

• Lead day‑to‑day support and operational management of CMMS (Blue Mountain), document systems, facilities and building systems and related enterprise business applications
• Oversee incident resolution, issue prioritization, system availability and service performance to maintain reliable application support and business continuity
• Coordinate troubleshooting and escalations with IT, vendors and support resources; monitor system health and recurring issues and maintain effective support procedures
• Manage the portfolio of application systems supporting US R&D Operations; maintain an inventory of supported systems, business owners, vendors, dependencies and support arrangements
• Partner with operations process owners to translate business workflows into application requirements, configuration standards and prioritized system improvements
• Coordinate application integrations and data exchanges with IT and vendors; monitor interface issues and resolve failures that affect operations workflows and reporting
• Establish data ownership and quality controls with operations stakeholders; oversee consistent master data, reporting definitions and system records to support reliable operational decisions
• Maintain lifecycle plans for operations application systems, including version currency, vendor support status, licensing needs and replacement priorities; coordinate capacity and resource planning with IT and Procurement
• Coordinate backup, recovery and continuity arrangements for operations application systems with IT and vendors; support recovery testing and confirm support coverage for critical operating periods
• Lead…