Clinical Research Fellow in Gastroenterology

Clinical Research Fellow in Gastroenterology

Applicants are invited to apply for the position of Clinical Research Fellow in IBD / Gastroenterology, based at Imperial College Healthcare NHS Trust and Imperial College London.

The appointee will be involved in a research project under the supervision of Dr. James Alexander and Prof. Nick Powell. It is an excellent opportunity for individuals with an interest in Inflammatory Bowel Disease (IBD) research. The successful candidate will be expected to register for a higher degree (MD or PhD).

A degree in Medicine (MBBS or equivalent) and full MRCP or equivalent is essential, as is full General Medical Council registration. You will need a minimum of experience as an ST4 in Gastroenterology.

Kindly note: Provisional interview date is 5th March 2026.

The research project is fully funded by a grant from Glaxo Smith Kline  to deliver a multicentre interventional trial of the recombinant zoster vaccine (Shingrix) in patients with IBD. The trial aims to determine if pausing IBD medication during immunisation results in enhanced immunological responses to vaccination.

The appointee will support the Imperial Clinical Trials Unit with patient recruitment and lead on laboratory analysis of antibody and cell-mediated immunity. The position will provide opportunities and training to employ cutting‑edge translational science, including gut microbiome and metabolomic platforms, to understand variability in vaccination responses. The project will also leverage UK‑wide collaborative networks to explore the critical issue of vaccination hesitancy in patients with IBD.

It is anticipated that the results of the project will be presented at national and international meetings, and published in high‑impact peer‑reviewed journals.

At Imperial College Healthcare you can achieve extraordinary things with extraordinary people, working with leading clinicians pushing boundaries in patient care.

Become part of a vibrant team living our values – expert, kind, collaborative and aspirational. You'll get an experience like no other and will fast‑forward your career.

Benefits include career development, flexible working, wellbeing, staff recognition scheme, Cycle to Work, car lease schemes, season ticket loan or membership options for onsite leisure facilities.

We are committed to equal opportunities and improving the working lives of our staff and will consider applications to work flexibly, part time or job share.

The appointed candidate will help manage patients with acute and chronic gastrointestinal disease (such as inflammatory bowel disease, gastrointestinal haemorrhage, gastrointestinal infection and cancer, motility and functional disorders) along with patients with general medical problems.

The post holder will be required to provide the clinical support and knowledge required for the day-to‑day delivery of the OVATION‑IBD trial. You should have a good understanding of IBD and trial methodology, be able to interpret findings and demonstrate understanding and limitations of study design and available data.

• On GMC registered/ licensed Medical Practitioner
• ALS Certificate
• Full MRCP (UK) or equivalent

• Higher research degree

• Experience in medical specialties and acute medical take at SHO level.

• Appropriate to job description

• Knowledge of NHS processes and pressures
• Experience of teaching students and junior medical staff
• Understanding of principles of clinical audit

• Clinical service development and research experience

• Able to speak and write English to the appropriate standard necessary to fulfil the job requirements

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous…