Senior Data Engineer

AI ACCELERATOR Most diseases are still poorly understood at a biological level. Despite decades of research, the causal mechanisms driving many conditions remain unclear, limiting our ability to identify the right targets, design the right interventions and bring the right medicines to patients. The AI Accelerator exists to change that. Based in London and sitting within Computational Innovation (@computational innovation), a global organisation spanning computational biology, human genetics, data excellence and AI, the Accelerator's mission is to build production-quality AI capabilities that deepen our understanding of disease biology and increase probability of success.

We do this by applying neural-based methods across the biomedical data landscape to integrate heterogeneous, multimodal data sources, infer biological relationships and embed causal thinking into what we build. The goal is not just to predict but to explain and understand why disease occurs. It could be electronic health records and medical imaging to support patient segmentation. It could be 'omics data to identify novel therapeutic targets.

It could be predicting transcriptional change for a given disease-causing variant. It could be simulating the effect of modulating a target of interest. None of this is possible without data. The quality, accessibility and engineering of biomedical data ultimately determine the quality of the models built upon them. The Data Engineering function provides the foundation on which the AI Accelerator operates by integrating diverse clinical, biological and real-world datasets into trustworthy, AI-ready assets that can support large-scale foundation model development and downstream scientific discovery.

THE POSITION We are seeking a Senior Staff Data Engineer to join Computational Innovation's AI Accelerator. In this role, you will own the data engineering architecture, standards and technical direction for the AI Accelerator, ensuring that our foundation-model ambitions are built upon high-quality data. You will define how diverse, multimodal, biomedical datasets are integrated and provisioned, creating the data foundation that enables model training, evaluation and deployment, supporting current research priorities and future scientific opportunities.

This is both a strategic and hands-on technical leadership role. You will define architectural standards and engineering practices, solve the most challenging data engineering problems yourself, and serve as the senior technical authority for data engineering within the AI Accelerator. As a senior member of the AI Enablement leadership team, you will help shape the direction of the function alongside the Senior Staff AI Infrastructure Engineer and Senior Staff MLOps Engineer.  

This is a unique opportunity to be part of a critical strategic initiative for a pharmaceutical company that invests heavily in research and development to discover and develop innovative therapies that can improve and extend lives in areas of high unmet medical need. Your work will directly influence how effectively we can understand disease, identify therapeutic opportunities and accelerate the development of innovative medicines for patients.

Key Responsibilities Set the technical direction, strategy and roadmap for data engineering, aligned to AI Accelerator priorities. Own the data engineering architecture for the AI Accelerator, defining and evolving a layered ("medallion"-style) architecture, feature and embedding provisioning patterns, and the harmonised multimodal data foundation that underpins model development. Establish data engineering standards and engineering practices, including data quality controls, testing, CI/CD for data, reproducibility standards, data contracts, metadata management and dataset versioning.

Deliver hands-on leadership on the most difficult and highest-impact data engineering challenges, including integrating novel and complex modalities such as genomics, transcriptomics, imaging, clinical and real-world datasets. Partner with the Data Excellence community and IT to align on governance, ontologies, metadata harmonisation, stewardship and shared enterprise data foundations. Establish ways of working and coach other team members, onboarding, mentoring and technically leading data engineers as the team scales, while acting as the senior escalation point for complex data engineering challenges.

Requirements PhD or MSc and equivalent experience in a STEM subject.…