Biosensor Research Scientist; Electrochemical sensors

About Level Zero

Level Zero is pioneering next‑generation biosensor technology for precise, real‑time monitoring of critical endocrine biomarkers. Recognised as one of the top 20 startups across all categories worldwide at Tech Crunch Disrupt 2024—and backed by top‑tier organisations like SOSV and Entrepreneur First—we’re pushing the boundaries of biochemistry and nanotechnology to revolutionise personalised health.

Founded by two seasoned engineers, we bring extensive experience in R&D, technical innovation, and commercial strategy to transform the way people monitor their health. Our mission is bold: to revolutionise health management by delivering clinical‑grade data directly to individuals, wherever they are.

We’re seeking driven innovators to join us in pushing the boundaries of biosensing and health tech, making personalised health monitoring a reality for everyone. To achieve this ambitious vision, we’re assembling the best team in the world—dedicated to turning cutting‑edge science into life‑changing, real‑world solutions.

We are excited to welcome a biosensor scientist with a strong background in electrochemical biosensor R&D and experience in working with aptamers to join our rapidly growing start‑up. The ideal candidate is expected to be proficient in bench and wet chemistry techniques. Moreover, they should have sound knowledge and experience in assay development, small molecule detection, and electrode surface modifications. It is essential for the candidate to have extensive experience in aptamer‑based electrochemical biosensor R&D, including the designs, operation principles, troubleshooting, and analysis.

This is a full‑time, in‑person role primarily based in London.

• Design, prototype, and optimise electrochemical biosensor systems, focusing on small molecule analytes and aptamer‑based recognition.
• Apply surface chemistry and electrode modification strategies to improve sensitivity, selectivity, stability, and biosensor performance in complex biological samples.
• Translate bio‑element–target interactions into measurable and reproducible sensor outputs through novel assay design.
• Apply a range of electrochemical methods (voltammetry, impedimetry, chronoamperometry, etc.) to characterize and evaluate biosensor function.
• Apply data‑driven approaches including Python‑based analysis and Design of Experiments (DoE) to streamline workflows.
• Troubleshoot technical and conceptual challenges systematically and propose innovative solutions to improve performance.
• Develop and maintain Standard Operating Procedures (SOPs) and ensure experimental reproducibility and compliance with quality standards.
• Collaborate effectively with cross‑functional teams (chemists, biologists, engineers, and data scientists) to advance biosensor prototypes from concept to application.
• Present results clearly through written reports, oral presentations, and scientific publications.
• Attend R&D‑related trainings and seminars for continuous updates on the latest trend in hormone sensing technologies.

• A Ph. D. degree in Electrochemistry, Analytical Chemistry, Biochemistry, Chemical/Materials Engineering or related discipline, with a focus in aptamer biosensors. Post‑doctoral experience will be a plus for this role.

• Proven hands‑on experience in biosensor design, electrochemical techniques, and surface chemistry optimisation.
• Proficiency in operating electrochemical instrumentation and analysing experimental data.
• Demonstrated expertise with biorecognition elements, particularly aptamers, for biosensor applications.
• Strong knowledge of small molecule detection in biological and/or environmental samples.
• Practical experience in handling and analysing biofluids.
• Excellent problem‑solving and troubleshooting skills.
• Creative and open mindset with the ability to explore and implement novel approaches.
• Strong interpersonal and communication skills, with experience working in multidisciplinary teams.

• Experience with Surface Plasmon Resonance (SPR), molecular docking, or structural modelling.
• Familiarity with automation, Python scripting, and…