Senior Research Engineer

IXICO plc (AIM: IXI), is a global leader in neuroscience imaging and biomarker analytics, using its proprietary AI-driven platform to help advance the treatment of neurological disorders and reduce the uncertainties associated with drug discovery, development and monitoring. As a key part of the global neurological disease research community, the Company has built a global reputation and 20-year track record as an end-to-end Imaging Contract Research Organisation (iCRO) working with leading pharma companies, innovative biotech's, disease consortia and non-profit organisations.

IXICO has supported hundreds of neurological clinical trials, analysed hundreds of thousands scans and built an expansive network of expert imaging centres around the world.

The IXICO Platform is tailor-made for neurological disease, reliably processing data from global trials, precisely measuring key imaging biomarkers associated with the identification, progression and treatment of diseases such as Alzheimer's, Huntington's and Parkinson's. Image data is interrogated by the Platform and IXICO's expert scientists translating complex data into clinically meaningful while minimizing data variability and increasing reproducibility.

Our people are empowered to enable us to achieve our company goals and their own personal development through the “4A” values at the heart of our culture:
Aspiration, Ability, Agility and Accountability.

To help us deliver our medical image analysis solutions to large clinical trials we are hiring a Senior Research Engineer on a permanent full-time capacity.

This role is focused on leading innovation within assigned work streams across IXICO's analytics portfolio, advancing the company's Integrate, Automate, Standardise strategy. The role holder is responsible for innovative development and the definition of analytical validation strategy across MRI, PET and adjacent CNS biomarkers taking assigned work streams from concept up to transition to cross functional teams for productisation. The role holder contributes to the wider R&D roadmap, including build-vs-buy assessment of third-party technologies, and represents IXICO's scientific work externally.

Single-point accountability is expected; the role holder acts as technical lead for their assigned work streams. While the role carries no line-management responsibility, the role holder holds authority over scope definition, methodology, experimental design, validation gating and continue/pivot/stop recommendations within assigned work streams.

The role sits within R&D with day-to-day operational and line management from the Director, R&D. Strategic direction is set by the CSO/CMO, to whom the role holder reports regularly on innovation progress and trajectory to ensure alignment with company-level scientific and product strategy.

• Lead the design, development and assessment of innovative analytics approaches across MRI and PET imaging as well as adjacent CNS biomarkers from hypothesis through proof-of-concept and analytical benchmarking.
• Define requirements, validation strategies and intended-use-aligned performance specifications for each workstream, providing input to Regulatory Affairs and Medical Affairs on validation design.
• Iteratively optimise prototype analysis algorithms, data models and pre-processing pipelines to research-grade reproducibility standards, and partner with the Analysis Products team on transition of mature methods into the productisation track.

• Act as technical lead for named work streams: define validation gates, set pre-agreed continue / pivot / stop criteria and learning milestones, and, where applicable, provide oversight for the work of contributing scientists and engineers assigned to those work streams.
• Own the innovation roadmap for assigned work streams in line with IXICO’S commercially led R&D prioritisation process.
• Contribute to the wider R&D Roadmap, providing input on dependencies, synergies and sequencing trade-offs between assigned work streams and IXICO's other product streams.
• Cr…