Clinical Biomarker Lead, Senior Scientist

Location: Greater London

## Clinical Biomarker Lead, Senior Scientist Apply locations:
Paris:
London time type:
Full time posted on:
Posted Todayjob requisition :
R-21893
*
* Title:

** Clinical Biomarker Lead, Senior Scientist
** Company:
** Ipsen Innovation (SAS)
** About Ipsen:
** Ipsen is a mid-sized global biopharmaceutical company with a focus on transformative medicines in three therapeutic areas:
Oncology, Rare Disease and Neuroscience. Supported by nearly 100 years of development experience, with global hubs in the U.S., France and the U.K, we tackle areas of high unmet medical need through research and innovation. Our passionate teams in more than 40 countries are focused on what matters and endeavor every day to bring medicines to patients in 88 countries.

We build a workplace that champions human-centric leadership and fosters a culture of collaboration, excellence and impact. At Ipsen, every individual is empowered to be their true selves, grow and thrive alongside the company’s success. Join us on our journey towards sustainable growth, creating real impact on patients and society!

For more information, visit us at
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* Job Description:

***
* Job Title:

** Clinical Biomarker Lead, Senior Scientist
** Division / Function:
** Early Development, Translational Sciences
*
* Location:

** London or Paris
** WHAT -*
* ** Summary & Purpose of the Position
** To develop and lead clinical biomarker strategies that enable data-driven decision-making across clinical development and maximize the value of Ipsen's oncology and rare disease portfolio. The Biomarker Lead serves as a strategic partner to cross-functional development teams, ensuring biomarker approaches are scientifically robust, aligned with program objectives, and support critical development milestones.

The position provides biomarker leadership from early clinical development through registration, defining data-generation strategies that inform patient selection, mechanism of action, clinical benefit, and regulatory decision-making. The role contributes expertise in biomarker development, validation and implementation while fostering innovative approaches that strengthen Ipsen's biomarker capabilities across therapeutic area
** s.
**** WHAT -*
* ** Main Responsibilities & Technical Competencies
*** Develop and lead clinical biomarker strategies across Ipsen's oncology and rare disease portfolio to support critical development and portfolio decisions.
* Define biomarker plans to support target engagement, pharmacodynamic and mechanistic understanding, patient stratification, and support efficacy assessment across clinical development.
* Provide strategic leadership for biomarker data generation from early clinical development through late-stage and registration-enabling studies, as appropriate.
* Select and apply the most appropriate biomarker technologies and analytical approaches to address program objectives, including cellular, tissue-based, genomic, transcriptomic, proteomic, and emerging platform technologies.
* Drive implementation of biomarker strategies within clinical studies, including development of protocols, schedules of activities, laboratory manuals, biomarker analysis plans, and study-related documentation.
* Provide scientific oversight of biomarker assay development, fit-for-purpose validation, and analytical performance assessments to ensure data quality and fitness for intended use.
* Collaborate with Clinical Development, Translational Pharmacology, Companion Diagnostics, Clinical Pharmacology, Biostatistics, Clinical Operations, Regulatory Affairs, and external partners to ensure successful execution and interpretation of biomarker activities.
* Lead the selection, oversight, and performance management of external laboratories, CROs, and other vendors supporting biomarker development and analysis.
* Contribute to biomarker components of statistical analysis plans and integrate biomarker findings into study interpretation and development strategy.
* Author, review, and contribute to biomarker sections of protocols, study reports, regulatory submissions, briefing documents, and health authority…