Director, Epidemiology & Evidence Strategy

52978

Posted: 11/08/2026london, United Kingdom

Contract

Director, Epidemiology & Evidence Strategy Europe, United States
Permanent
Permanent | Global Pharmaceutical Company Overview
We are partnering with a large, global pharmaceutical organisation to appoint a Director, Epidemiology & Evidence Strategy to lead epidemiological input across a confidential portfolio of late-stage assets. This is a senior scientific leadership role, responsible for shaping the epidemiological evidence strategy that underpins regulatory submissions, risk management, and lifecycle planning across multiple indications.

Key Responsibilities
1. Epidemiological Strategy & Leadership Set the overarching epidemiology strategy across the portfolio, aligning with regulatory, clinical, and commercial objectives
Serve as the senior scientific authority on disease burden, natural history, and background incidence/prevalence for priority indications
Represent epidemiology at senior governance forums, advising on programme-level risk and evidence gaps
Build and lead a team of epidemiologists, mentoring junior staff and setting scientific standards across studies
2. Study Design & Evidence Generation Design and oversee observational studies, including natural history studies, disease registries, and post-authorisation safety/efficacy studies
Provide expert methodological oversight on epidemiological approaches, including bias mitigation, confounding control, and causal inference frameworks
Lead development of study protocols, statistical analysis plans, and epidemiological sections of regulatory submissions
Ensure epidemiological rigor across all evidence-generation activities, from concept through to publication
3. Regulatory & Cross-Functional Engagement Author and review epidemiological content for regulatory submissions, risk management plans, and health authority responses
Act as the epidemiology lead in interactions with regulatory agencies, responding to scientific queries
Partner closely with Biostatistics, Pharmacovigilance, Medical Affairs, and Health Economics to ensure epidemiological evidence is integrated into broader evidence packages
Provide epidemiological input into signal detection and benefit-risk assessment activities
Impact of the Role Shape the epidemiological evidence foundation for a confidential multi-indication portfolio
Strengthen the organisation's scientific credibility with regulators through rigorous epidemiological input
Build internal epidemiology capability and governance standards
Influence long-term lifecycle and risk management strategy across therapeutic areas
Your Profile

PhD in Epidemiology (or closely related discipline) required
Extensive experience (12+ years) in epidemiology within pharmaceutical, biotech, or public health settings, including senior/leadership experience
Deep expertise in observational study design, causal inference, and pharmacoepidemiological methods
Demonstrated experience authoring epidemiological content for regulatory submissions and interacting with health authorities
Track record of leading and developing epidemiology teams
Strong scientific writing and publication record
Excellent stakeholder management skills, with experience presenting to senior governance and regulatory bodies
Director, Epidemiology & Evidence Strategy
52731 | Posted: 11/08/2026

Europe, United States
Permanent
Permanent | Global Pharmaceutical Company Overview
We are partnering with a large, global pharmaceutical organisation to appoint a Director, Epidemiology & Evidence Strategy to lead epidemiological input across a confidential portfolio of late-stage assets. This is a senior scientific leadership role, responsible for shaping the epidemiological evidence strategy that underpins regulatory submissions, risk management, and lifecycle planning across multiple indications.

Key Responsibilities
1. Epidemiological Strategy & Leadership Set the overarching epidemiology strategy across the portfolio, aligning with regulatory, clinical, and commercial objectives
Serve as the senior scientific authority on disease burden, natural history, and background incidence/prevalence for priority indications
Represent epidemiology at senior governance forums, advising on programme-level risk and evidence gaps
Build and lead a team of epidemiologists, mentoring junior staff and setting scientific standards across studies
2. Study Design & Evidence Generation Design and oversee observational studies, including natural history studies, disease registries, and post-authorisation safety/efficacy studies
Provide expert methodological oversight on epidemiological approaches, including bias mitigation, confounding control, and causal inference frameworks
Lead development of study protocols, statistical analysis plans, and epidemiological sections of regulatory submissions
Ensure epidemiological rigor across all evidence-generation activities, from concept through to publication
3. Regulatory & Cross-Functional Engagement Author and review…