Senior ​/ Principal Bioinformatician

Join a global biopharmaceutical organisation dedicated to transforming patient outcomes across multiple disease areas. You'll be part of a science‑driven environment that values innovation, collaboration, and meaningful impact and work with highly experienced colleagues.

This is a long term contract role (initially 1 year but likely to extend) within a well-established team where you will be reporting into senior bioinformatics leadership.

The company has a collaborative and innovative atmosphere, where you will be supporting multiple projects within translational and clinical development across several therapy areas.

The role is hybrid, with c.3 days per week from home, though this can be negotiable for the right candidate.

The role can be at either Senior Bioinformatician or Principal Bioinformatician grade and you will be working on drug development projects, playing a key role in generating biological insights from clinical stage omics data to support decision making across the therapeutic portfolio.

Major responsibilities will include:

• Processing, analysing, and interpreting multi‑omic (RNAseq, NGS, proteomic, etc) datasets from clinical studies
• Deriving mechanistic, biological, and treatment related insights from patient‑level data
• Developing and optimising analysis methods, pipelines, and computational workflows
• Ensuring reproducibility and best practice documentation for code and analyses
• Drafting high quality reports and contributing to scientific publications
• Integrating omics outputs with clinical variables to enhance understanding of drug effects
• Operating autonomously while collaborating with cross‑functional scientific teams

A strong candidate will bring experience in clinical bioinformatics along with:

• An MSc / PhD (or equivalent experience) in bioinformatics, computational biology, statistical genetics, biology, or a related subject
• Good expertise in analysing bulk and single‑cell RNA‑seq from complex or clinical studies, with a significant preference for candidates who have done this in an industry (pharma, biotech, CRO) setting
• Experience with multi‑omics integration, functional interpretation, and pathway analytics
• Strong computational skills, including HPC, cloud platforms, and containerisation tools
• Proficiency in R and other commonly used bioinformatics programming languages
• Solid grounding in statistics, data mining, and biological data visualisation
• Ability to clearly communicate findings to both expert and non‑expert audiences

As well as an excellent opportunity to progress and develop your career within an innovative and collaborative work environment you’ll be making a significant impact on the next generation of medicines and the patients they treat.

You’ll also have plenty of flexible working options and a generous pay package.