Senior Laboratory Research Scientist – Flow Cytometry

Salary

From £47,080, plus benefits, subject to skills and experience

Senior Laboratory Research Scientist – Flow Cytometry

Andy Riddell, Head of Flow Cytometry

16/Sept/ GMT

Full-time, permanent position on Crick terms and conditions of employment.

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions.

We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting‑edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

The Flow Cytometry Science Technology Platform at the Francis Crick Institute provides researchers with access to cutting‑edge cell analysis and sorting technologies, alongside expert scientific advice and technical support. Supporting a diverse range of biomedical research, our team combines advanced instrumentation with specialist expertise to help researchers design, optimise and deliver high‑quality flow cytometry experiments.

We are seeking an experienced Flow Cytometry Specialist to join our team and help deliver an outstanding service to researchers across the Crick. You will provide expert advice on experimental design, multicolour and spectral flow cytometry, cell sorting and data analysis, while operating and maintaining a wide range of advanced instrumentation. A key part of the role will also be hands‑on troubleshooting – from optimising the latest technologies to maintaining complex legacy instruments that require creative technical problem‑solving.

This is an exciting opportunity for an experienced flow cytometry professional who enjoys solving technical challenges, supporting researchers and helping develop the capabilities of a world‑class scientific facility.

• Providing expert scientific and technical advice to researchers using flow cytometry.
• Supporting experimental design, multicolour and spectral panel design, assay optimisation and troubleshooting.
• Operating, maintaining and troubleshooting high‑speed cell sorters and multi‑laser analysers.
• Supporting the introduction, validation and optimisation of new technologies and workflows.
• Analysing and interpreting flow cytometry data using specialist software and computational tools.
• Training and mentoring researchers and junior team members in flow cytometry best practice.
• Supporting laboratory operations, documentation, equipment management and continuous improvement across the facility.

• Essential: A PhD with at significant practical experience in flow cytometry, or a BSc (Hons) with substantial relevant experience gained within a core facility, research or company setting.
• Extensive hands‑on experience operating high‑speed cell sorters and multi‑laser analysers.
• Experience supporting flow cytometry experimental design, multicolour panel design and troubleshooting.
• Experience with spectral flow cytometry.
• Strong technical ability and enthusiasm for maintaining and troubleshooting complex flow cytometry instrumentation.
• Proficiency with flow cytometry acquisition and analysis software such as FACSDiva and Flow Jo.
• Experience developing SOPs and risk assessments and training or mentoring researchers.
• Excellent communication, organisational and collaborative working skills.
• Desirable: Experience with instrument engineering and advanced troubleshooting, including…