Senior Laboratory Research Scientist; Papayannopoulos Lab

Location

The Francis Crick Institute, Midland Road, London

The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world‑class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. To learn more about the Crick,  .

We are seeking a highly motivated Senior Laboratory Research Scientist (SLRS) to contribute to cutting‑edge research investigating the molecular and cellular mechanisms that regulate innate immune responses in health and disease. Working within a collaborative and multidisciplinary research environment, you will design and deliver innovative experimental studies using in vitro and in vivo models, while supporting the wider research programme through technical expertise, mentoring and laboratory coordination.

This is an exciting opportunity for an experienced immunologist to combine hands‑on research with scientific leadership and operational responsibilities within a world‑leading biomedical research institute.

• Designing and carrying out independent research using in vitro systems and mouse models of disease.
• Applying a range of molecular, cellular and biochemical techniques, including flow cytometry, CRISPR, microscopy and transcriptomic analysis.
• Analysing experimental data and contributing to high‑impact publications and scientific presentations.
• Mentoring PhD students and supporting the training of junior researchers.
• Collaborating with researchers across the Crick and external partners to advance immunology research.
• Supporting laboratory operations, including reagent and animal stock management, equipment coordination and ensuring compliance with health and safety standards.

• PhD in immunology, infection biology, biochemistry, cell biology or a related discipline, or be in the final stages of PhD submission.
• Strong knowledge of immunology, biochemistry and cell biology.
• Experience working with molecular, cellular and mouse models of disease.
• Evidence of scientific publications or submitted manuscripts.
• Strong experimental design, organisational and collaborative working skills.
• Experience mentoring or supporting students and junior researchers.
• Enthusiasm for innovative science and a strong drive to contribute to high‑quality research.

We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We're not afraid to do things differently. We are open. We're highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community. At the Crick, we believe that diversity and inclusion are essential to driving innovation and scientific discovery.

We value our team members and are proud to offer an extensive range of benefits to support their well‑being and development. You can find out more about what we offer here .

From £47,080 plus benefits, subject to skills and experience