Sr. Research Scientist, Principal Research Scientist, Research Investigator

Overview

Cambrex is seeking to fill multiple openings at various levels (including Sr. Research Scientist, Principal Research Scientist, Sr. Principal Research Scientist, and Research Investigator) with highly motivated individuals for the Process Chemistry department. Individuals in these positions perform routine and complex organic synthesis, purification, and analytical evaluation of materials as part of a process chemistry research and development team. The chemists will optimize synthetic routes to active pharmaceutical ingredients for purity, reproducibility, scalability, and yield.

Experience in process chemistry research and development is desirable. Individuals in these positions will design and propose new synthetic routes to drug substances and may be asked to lead the process chemistry portion of customer projects and potentially a group of process chemists. They will frequently present work internally and externally to clients or regulatory agencies.

Known for our scientific and manufacturing excellence, as well as our strong customer focus, we offer a range of career opportunities across our global network of locations. Together with our customers, we aim to improve the quality of life for patients around the world.

• Perform multistep organic syntheses, isolation, and purification of targeted products independently. Contribute to the strategic approach used to optimize reactions, isolations, and purifications.
• Proficiently conduct analysis of starting materials, reaction mixtures, intermediates and products using appropriate instrumentation.
• Work closely with other chemistry and analytical laboratory staff to coordinate project activities and resource usage.
• Routinely generate summaries and reports on completed experimental work for internal and external use. Routine presentation of experimental work for internal meetings and teleconferences with customers.
• Work to ensure that teamwork and cooperation exists within the group at all times.
• Conduct laboratory operations in a safe manner. Maintain familiarity with the company’s chemical hygiene plan. Exhibit safety awareness and safe work practices.
• Follow responsible actions regarding chemical disposal. Maintain compliance with all regulations at the federal, state, and local levels.
• Address routine administrative requirements in a timely fashion.
• Demonstrate effective communication skills (both written and oral). Participate in project team meetings with customers.
• Work closely with manufacturing and GMP operations to coordinate project-related equipment and activities. Assist in the transfer of processes to the manufacturing team.
• Independently design and propose new synthetic processes to produce the drug substance.
• May act as process chemistry lead for customer projects. Identify critical questions to be answered and set priorities for the process chemistry team.
• Maintain familiarity with applicable literature including organic chemistry and techniques.
• Participate in setting strategy and timing needed for customer proposal requests.
• Work closely with other chemistry and analytical laboratory staff to coordinate project activities and resource usage.
• Routinely generate summaries and reports on completed experimental work for internal and external use. Oral and written presentation of experimental work for internal meetings and teleconferences with customers.
• Performs other related duties as assigned.

• Senior Research Scientist - Specific Skill & Competency Requirements: advanced knowledge in synthetic chemistry transformations, reaction mechanisms and retrosynthetic analysis; developing knowledge of GMP/ICH guidelines; ability to design experiments and contribute ideas; strong safety practices; recognized as a technical expert; ability to publish or present externally.
• Principal Research Scientist - Specific Skill & Competency Requirements: leading edge knowledge in advanced synthetic, mechanistic and retrosynthetic analysis; developing knowledge of process chemistry and drug substance manufacturing; GMP/CMC/ICH guidelines experience; ability to design and execute projects; strong literature use; safety…