Clinical Genomics Variant Scientist

Clinical Genomics Variant Scientist

Location:

Los Angeles, CA
Job #27905

Work Hours:

Monday – Friday, 8:00am – 5:00pm

Employment Type:

2 – Staff
- Career
Duration:
Indefinite
Posted Date:
December 29, 2025

The Molecular Diagnostics Laboratory is seeking an experienced Variant Scientist to join our clinical team. In this critical role, you will curate and interpret germline and somatic variants and prepare high‑quality clinical reports derived from exome and targeted cancer sequencing assays. You will contribute to variant classification, test development efforts, and clinical research projects that advance precision medicine for patients across UCLA Health and beyond.

• Review and assess patient clinical notes and sequencing data from high‑complexity molecular assays, including Clinical Exome Sequencing, Solid Tumor Sequencing Panels, and Hematologic Malignancy Sequencing Panels.
• Perform variant curation and interpretation using established guidelines and evidence‑based resources.
• Draft and refine clinical reports, ensuring accuracy, clarity, and clinical relevance.
• Develop and update SOPs for variant curation, interpretation, and reclassification workflows.
• Participate in submitting curated variants to public databases (e.g. Clin Var) and contribute to quality improvement and test development initiatives.
• Collaborate with clinicians, genetic counselors, and laboratory staff to support accurate and timely reporting.
• Contribute to clinical research projects and assist in implementing new molecular diagnostic assays.

$ – $ per year

UCLA Health is an Equal Opportunity Employer.