Postdoctoral Research Fellow

The laboratory of Dr. Hui Zhang in the Division of Immunotherapy, Department of Surgery, and Brown Cancer Center at the University of Louisville School of Medicine is seeking a highly motivated and dedicated scientist for a Postdoctoral Research Fellow position.

Research in the Zhang Laboratory focuses on exploring the function of double-negative T (DN T) cells in antitumor immunity and cancer immunotherapy. DN T cells play a pivotal role in initiating antitumor immune responses and shaping the tumor microenvironment. Understanding the underlying mechanisms will enable the development of a novel paradigm for cancer immunotherapy. The successful candidate will play an integral role in advancing cutting-edge research funded by an NIH/NCI R01 grant.

• Design and execute experiments related to DN T cells, tumor immunology, and cancer therapies, followed by data analysis.
• Draft manuscripts for publication and prepare presentations for scientific meetings.
• Assist in training and mentoring lab members, including graduate and undergraduate students, research interns, and technicians.
• Collaborate with other lab members to integrate data across multiple platforms.
• Maintain accurate and up-to-date experimental records.
• Ph.D. in Biomedical Sciences, such as Immunology, Cancer Biology, Cell Biology, or a related field.
• Extensive hands-on experience in molecular biology, cell biology, and immunology techniques.
• Proficiency in using animal models, flow cytometry, immunofluorescence, and in vitro bioassays.
• Strong skills in experimental design, data analysis, and troubleshooting.
• Ability to communicate research findings effectively in written and oral formats.

• Extensive knowledge and expertise in bulk/single-cell RNA sequencing and bioinformatics.
• Knowledge of cancer immunotherapy, tumor microenvironment dynamics, and immune cell functions.
• Project planning and execution.
• Manuscript preparation of research findings.
• Statistical analysis, data interpretation and trouble shooting.
• Organized – manages time effectively, keeps tasks appropriately prioritized.
• Critical Thinking – ability to think through issues and identify appropriate options.
• Work Ethic – motivated, diligent, industrious, and persistent in the workplace, stays on tasks to completion, works at a pace sufficient to ensure optimal efficiency.
• Interpersonal – can build effective, strong working relationships with employees, colleagues, management and vendors through trust, communication, and credibility.
• Teamwork – ability to work with others.

• Lab based environment
• Occasionally:
  Works with poor ventilation or with regular exposure to odors
• Occasional exposure to infectious material/diseases
• Regular exposure to radiation, chemicals, solvents
• Requires balancing to prevent falling or erratic movement
• Light lifting or carrying 25 lbs. or less
• Moderate lifting or carrying 26-50 lbs.
• Constantly:
  Normal office situation; requires good near or distant vision
• Requires distinguishing colors and/or depth perception to judge distances
• Frequently:
  Typically sitting at a desk or table
• Intermittently sitting, standing, stooping
• Typically standing and/or walking
• Requires handling by seizing, holding, grasping, or turning hands, but without finger dexterity; requires good hearing and tactile perception to perceive objects by sensing size, shape, temperature, or texture

The above statements are intended to describe the general nature and level of work being performed by individuals assigned to this job. It is not intended to be an exhaustive list of all duties and responsibilities required of individuals in this job. Other duties may be assigned as determined by management.

Equal Employment Opportunity:
The University of Louisville is an equal opportunity, affirmative action employer, and is committed to providing employment opportunities to all qualified applicants without regard to race, sex, age, color, national origin, ethnicity, creed, religion, disability, genetic information, sexual orientation, gender, gender identity and expression, marital status, pregnancy, or veteran status.

If you require assistance or accommodation with our application process due to an impairment or disability, please email the contact listed above directly, or reach out to the Employment team at employment or . Assistance and Accommodations Computers are available for application submission at the Human Resources Department located at 215 Central Avenue, Ste 205 - Louisville, Kentucky 40208.