×
Register Here to Apply for Jobs or Post Jobs. X

Director Enterprise Architecture

Job in Macclesfield, Cheshire, SK11, England, UK
Listing for: AstraZeneca
Full Time position
Listed on 2026-02-12
Job specializations:
  • IT/Tech
    Systems Engineer, Cloud Computing, IT Project Manager, AI Engineer
Job Description & How to Apply Below

Introduction to role

Are you ready to develop an enterprise architecture that strengthens product quality and speeds up the provision of medications to patients worldwide? In this role, you will lead the end-to-end architecture across Pharmaceutical Technology, Quality Control, and Global Quality Assurance—linking datasets, artificial intelligence and machine learning solutions, applications, and platforms to clear business outcomes in a highly regulated environment.

From day one, you will develop a vision for architecture spanning one to five years and bring coherence to a sophisticated global portfolio. Can you see yourself simplifying and standardizing how we assure product quality across sites, minimizing exposure and expenses while growing agility? You will create the foundations that enable faster, safer decisions from lab to plant to release.

You will join an experienced architecture community that moves quickly, challenges how work gets done, and unites teams with varied strengths behind pragmatic standards. Your judgment will guide strategic choices, your governance will unlock value at pace, and your leadership will build the capabilities that keep our technology ecosystem resilient and ready for what’s next.

Accountabilities

Provide coordinated compose mentorship throughout Business, data science, intelligent systems, application development, and technological areas related to pharmaceutical tech, quality checking, and international quality assurance, ensuring solutions deliver measurable capability uplift.

Architecture Strategy and Roadmaps:
Define and own the develop principles, protocols, and roadmaps covering a timeframe spanning from one to as many as five years. Align them with corporate targets and regulatory needs. Set the North Star and sequence investments that improve value.

Strategic Decision Authority:
Act as the authority for major architecture decisions; approve solution builds, guide segment architectures, and ensure builds balance speed, risk, and cost.

Portfolio Simplification and Risk Reduction:
Continuously align capabilities to current objectives; rationalize and simplify to reduce technical risk and TCO while improving resilience and accuracy of data.

Governance and Cross-Functional Engagement:
Participate in steering teams, design authorities, and standards forums; bring clarity to trade-offs and ensure disciplined, outcome-focused decision-making.

Trend Sensing and Thought Leadership:
Examine sector and business environment developments relevant to your domain; translate insights into actionable mentorship and investments that keep us ahead.

Standards, Procedures, and Tools:
Coordinate the building and adoption of EA guidelines, workflows, and instruments; embed compliance validation and reliable data practices as a fundamental element.

External Partnerships and Product Evaluation:
Establish strategic collaborations with major providers and integration specialists; evaluate products, develop cases, and secure value through informed choices.

Lead 5 to 8 architects and a wider matrix community. Mentor, manage performance, develop expertise, and build communities of practice to increase impact.

Work globally across sites and functions. Partner with research and development, production, technical operations, and distribution teams. Ensure delivery of consistent, high-quality architectures across complex, large-scale environments.

Essential Skills/Experience
  • Proven experience providing enterprise design leadership across Business, Data, AI/ML, Application, and Technology within Pharmaceutical Technology, QC, and Global QA.
  • Demonstrated ability to define architecture strategy, standards, and 1–5 year roadmaps aligned to business priorities and supervised operating requirements.
  • Authority to make and govern strategic architecture decisions; experience signing off solution blueprints and guiding segment architectures.
  • Track record of continuously aligning capabilities with business objectives, rationalizing and simplifying portfolios to reduce risk and cost.
  • Active participation in cross-functional decision-making bodies (e.g., project steering teams, technical design authorities)…
Note that applications are not being accepted from your jurisdiction for this job currently via this jobsite. Candidate preferences are the decision of the Employer or Recruiting Agent, and are controlled by them alone.
To Search, View & Apply for jobs on this site that accept applications from your location or country, tap here to make a Search:
 
 
 
Search for further Jobs Here:
(Try combinations for better Results! Or enter less keywords for broader Results)
Location
Increase/decrease your Search Radius (miles)

Job Posting Language
Employment Category
Education (minimum level)
Filters
Education Level
Experience Level (years)
Posted in last:
Salary