Senior Antibody Scientist
Listed on 2026-07-21
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Research/Development
Research Scientist
Senior Antibody Engineer (Team Lead)
Permanent, full-time, onsite.
Location:
Macclesfield
Up to c £50,000 depending on experience. c £38,000 for recent PhD holders.
Our client are a multi-national drug discovery organisation providing a range of research services and internal drug discovery programmes across a variety of disease areas and drug modalities. They are currently seeking to expand their protein science team with the addition of a full-time and permanent Senior Antibody Engineer. This role will have potential for line management, depending on the seniority of the successful candidate.
My client will consider a range of seniorities for this position. This will include those with several years of industry experience, several years of post‑doctoral / postgraduate experience or straight PhD students. Salary and responsibilities will vary depending on the experience of the successful candidate.
Responsibilities- Leading on therapeutic antibody (and potentially other biologics including TCR) lead optimisation projects.
- Lead on antibody and biologics design projects focused on affinity maturity, humanisation and manufacturing feasibility. This will most be using in silico approaches, not wet lab.
- Option to lead a small team of scientists (2–4). This will depend on seniority of the successful candidate.
- Managing projects from start to completion, providing regular data and progress updates to clients and stakeholders via presentations and meetings.
- Working on multiple projects simultaneously.
- PhD in a biological discipline, MSc, BSc or equivalent are also fine (essential).
- Several years of post‑doctoral / post‑graduate experience specifically in lead optimisation stages for antibodies (affinity maturation, humanisation etc) (essential – straight PhD studies will be considered if their doctoral research is in this area).
- In silico experience for structural and genetic analysis (essential).
- Proven experience in leading complex scientific projects (essential).
- Prior line management experience of junior scientists (desired).
- Prior experience in working on client‑facing projects (desired).
- Experience in antibody expression and purification (desired).
- Must have right to work in the UK without need for visa sponsorship now or the future (essential).
As an established global organisation, our client is able to offer a competitive salary, progression options and benefits package including private pension.
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