LC​/MS Sample Prep Scientist

Talentmark are recruiting for a LC-MS Sample Prep Scientist to join a precision medicine company based near Manchester on a permanent basis.

Company:
Our client is developing next-generation diagnostic tests to help clinicians prescribe the right drug, for the right patient, at the right time. They are developing LC-MS proteomic biomarker discovery platforms and clinical assays to predict drug response in a clinical setting.

The Role:

You will support the development of clinical assays for biomarkers by preparing samples for LC-MS analysis

Responsibilities:

• Perform analysis of clinical samples to identify new biomarkers for emerging drugs of interest.
• Coordinate with management and other members of the technical team so that sample analyses are scheduled and performed in a timely manner.
• Assist with the experimental component of projects, including experimental design, sample preparation optimisation and automation, and data interpretation.
• Assist with the maintenance of cell line stocks and generation of samples for method development and QC.
• Make process improvements and project efficiencies wherever possible and contribute freely to the team environment in a manner conducive to the success of company goals.
• Work with the product development team and quality manager to ensure appropriate systems, monitoring and documentation are in place during development of a test.
• Handling and management of samples, including organising storage, database logging and safe disposal.

Your Background:

• Educated to PhD level in a relevant field such as proteomics or protein biochemistry applied to the investigation of mammalian cell biology.
• Hands-on experience in sample preparation using proteomic workflows for LC-MS/MS analysis.
• Experience working with multiple sample types (e.g. cell lines, blood, fresh-frozen and/or FFPE tissue).
• Experience working to GLP standards and/or in an HTA-qualified environment.
• Knowledge and understanding of fundamental principles of biochemical and molecular biological systems.
• Ability to plan and execute experiments and analyses: possesses strong problem-solving abilities with an analytical mindset, and a logical approach to troubleshooting technical challenges.

Apply:

For more information, or to apply for this position please contact Mary Bolt on (phone number removed) or email (url removed). Please quote job reference (phone number removed) in all correspondence.

It is essential that applicants hold entitlement to work in the UK