Principal Scientist
Job in
Macclesfield, Cheshire, SK11, England, UK
Listed on 2025-12-22
Listing for:
Nexus Life Sciences
Full Time
position Listed on 2025-12-22
Job specializations:
-
Science
Research Scientist, Pharmaceutical Science/ Research, Analytical Chemist, Data Scientist
Job Description & How to Apply Below
Principal Scientist
Salary:
Up to £60,000 (based on experience)
Job Type: Permanent
Overview
An innovative pharmaceutical company is seeking an experienced Principal Scientist to join their analytical team at their cutting-edge facility. The principal scientist will be responsible for leading lab-based work to support synthetic route development for APIs.
Principal Scientist Responsibilities:
* Lead and guide analytical development on complex chemistry projects for pharmaceutical / Biotechnology clients working in multidisciplinary teams.
* Develop and validate analytical methods (HPLC / LCMS / GCMS / NMR / XRD etc.) to support early, mid and late phase synthetic route development for APIs.
* Provide expert analytical advice to process chemistry colleagues.
* Interface with clients to communicate data, results, and conclusions effectively.
Qualifications
* A higher or bachelor’s degree in Chemistry, Analytical Chemistry, or a related scientific discipline.
* Strong expertise in Analytical Chemistry, with hands-on experience in LC/GC method development and other analytical methodologies (e.g., NMR, MS, IR, XRD).
* A proven track record in analytical project leadership.
* Knowledge of regulatory requirements for developing and validating LC/GC methods for APIs, intermediates, and raw materials.
* Experience in investigating out-of-specification and atypical results.
* Experience in analytical support for early, mid, or late-phase API development.
Benefits
* Competitive salary up to £60,000 (based on experience).
* Comprehensive benefits package, including company pension, health and life insurance.
* 25 days of annual leave, plus enhanced family leave.
* Flexible working hours to support work-life balance.
* The opportunity to work in a state-of-the-art facility at one of the UK’s leading Biotech & Life Science Parks.
* A chance to collaborate with global teams and work on innovative projects that make a real difference.
For more information on the role, I can share a job specification for review.
We are an Equal Opportunities employer and welcome applications from all qualified individuals, regardless of race, sex, disability, religion/belief, sexual orientation, or age.
Please note:
Applicants must have the right to work in the UK. Unfortunately, we are unable to sponsor visas for this role
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