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Principal Scientist

Job in Macclesfield, Cheshire, SK11, England, UK
Listing for: Nexus Life Sciences
Full Time position
Listed on 2025-12-22
Job specializations:
  • Science
    Research Scientist, Pharmaceutical Science/ Research, Analytical Chemist, Data Scientist
Salary/Wage Range or Industry Benchmark: 50000 - 60000 GBP Yearly GBP 50000.00 60000.00 YEAR
Job Description & How to Apply Below
Job Title:

Principal Scientist

Salary:
Up to £60,000 (based on experience)

Job Type: Permanent

Overview

An innovative pharmaceutical company is seeking an experienced Principal Scientist to join their analytical team at their cutting-edge facility. The principal scientist will be responsible for leading lab-based work to support synthetic route development for APIs.

Principal Scientist Responsibilities:

* Lead and guide analytical development on complex chemistry projects for pharmaceutical / Biotechnology clients working in multidisciplinary teams.

* Develop and validate analytical methods (HPLC / LCMS / GCMS / NMR / XRD etc.) to support early, mid and late phase synthetic route development for APIs.

* Provide expert analytical advice to process chemistry colleagues.

* Interface with clients to communicate data, results, and conclusions effectively.

Qualifications

* A higher or bachelor’s degree in Chemistry, Analytical Chemistry, or a related scientific discipline.

* Strong expertise in Analytical Chemistry, with hands-on experience in LC/GC method development and other analytical methodologies (e.g., NMR, MS, IR, XRD).

* A proven track record in analytical project leadership.

* Knowledge of regulatory requirements for developing and validating LC/GC methods for APIs, intermediates, and raw materials.

* Experience in investigating out-of-specification and atypical results.

* Experience in analytical support for early, mid, or late-phase API development.

Benefits

* Competitive salary up to £60,000 (based on experience).

* Comprehensive benefits package, including company pension, health and life insurance.

* 25 days of annual leave, plus enhanced family leave.

* Flexible working hours to support work-life balance.

* The opportunity to work in a state-of-the-art facility at one of the UK’s leading Biotech & Life Science Parks.

* A chance to collaborate with global teams and work on innovative projects that make a real difference.

For more information on the role, I can share a job specification for review.

We are an Equal Opportunities employer and welcome applications from all qualified individuals, regardless of race, sex, disability, religion/belief, sexual orientation, or age.

Please note:

Applicants must have the right to work in the UK. Unfortunately, we are unable to sponsor visas for this role
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