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Bioinformatics Engineer

Job in Madison, Dane County, Wisconsin, 53701, USA
Listing for: Exact Sciences
Full Time position
Listed on 2026-01-02
Job specializations:
  • Software Development
    Software Engineer, AI Engineer
Job Description & How to Apply Below
Position: Staff Bioinformatics Engineer

Staff Bioinformatics Engineer at Exact Sciences summary:

The Staff Bioinformatics Engineer leads and develops complex software solutions for processing Next Generation Sequencing data aimed at cancer diagnostics. This role involves designing cloud-based bioinformatics tools, managing data workflows, and mentoring junior engineers within a collaborative scientific environment. The position requires strong software development skills, cloud expertise, and the ability to communicate technical designs effectively across the organization.

Help us change lives

At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others.

Position Overview

The Staff Bioinformatics Engineer is largely self-driven, working in collaboration with others on one or more projects which are extremely complex in scope. This role is responsible for successfully leading the planning and execution of projects. Working in a team setting, this role will contribute to the design and implementation of new software solutions to process and interpret Next Generation Sequencing (NGS) data for the purpose of cancer diagnostics.

This position will be involved in producing software to orchestrate and execute analysis workflows as well as building new bioinformatics tools that operate directly on scientific data. Leveraging the latest data platforms and technologies together we will build cloud-based solutions ready for a production environment.

We are seeking candidates with a strong focus on quality throughout their work and who place high value on peer review, software testing and documentation. The successful candidate will join a geographically distributed team of highly motivated bioinformaticians and developers at the forefront of cancer diagnostics and be required to collaborate closely with scientists, IT and others create solutions to meet the underlying need.

During recruitment we prioritize talent over experience with specific technologies and will provide opportunities to learn and experiment with any technology that is new to the successful candidate. The Staff Bioinformatics Engineer helps develop the timeline and plan for new assignments/projects. As a technical expert with deep knowledge and thorough understanding of the bioinformatics engineering, this role provides technical guidance and mentorship to junior engineers in the Bioinformatics group.

Essential Duties

Include, but are not limited to, the following:

  • Contribute to the development of software tools to support the bioinformatics workflow operations of Exact Sciences.
  • Contribute to the design and architecture of cloud-based software solutions.
  • Design and implement data storage solutions for experimental data and analysis results.
  • Provide guidance and mentorship to the team (to other developers and beyond) on software development practices.
  • Transition early development code into a production environment.
  • Communicate software system designs to stakeholders across the organization.
  • Build and maintain cloud infrastructure to support data analysis pipelines.
  • Establish best practices for effective and cost-efficient use of cloud resources.
  • Interact with the wider Exact Sciences organization on cloud computing.
  • Produce high quality documentation of software and infrastructure.
  • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
  • Support and comply with the company’s Quality Management System policies and procedures.
  • Exercise excellent team-working skills with ability to complete collaborative projects on time and within budget.
  • Exercise excellent verbal and written communication skills with the ability to communicate complicated ideas and information effectively at all levels.
  • Demonstrated ability working towards challenging goals in a fast-moving environment where on-time delivery of results is a high priority.
  • Demonstrated ability working in a fast…
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