Senior Manager, GxP GDBT Service and Business Systems

Overview

The Senior Manager, GxP GDBT Service and Business Systems leads the strategy and compliance of core manufacturing systems in Hertfordshire. This permanent, full-time role sits within a global pharmaceutical organisation, focusing on the resilience and performance of platforms that support medicine supply. The position requires strategic oversight of technology and quality integration in a hybrid working pattern.

• Develop and deliver the site's digital and business systems strategy.
• Lead the performance, resilience and compliance of GxP-regulated business systems.
• Drive digital transformation and smart manufacturing initiatives.
• Partner with senior stakeholders across Manufacturing, Quality, Engineering, Supply Chain and Global IT.
• Lead a specialist team covering Manufacturing Systems, Operational Technology (OT), Laboratory Systems, Supply Chain Systems, Computer System Validation (CSV), Serialization and IT Services.
• Own the digital portfolio, prioritising investments and overseeing strategic programmes.
• Ensure business continuity, regulatory compliance, audit readiness and data integrity across critical manufacturing systems.
• Build high-performing teams while developing capability and driving continuous improvement.
• Represent the manufacturing site within regional and global technology governance forums.

• Significant leadership experience within pharmaceutical manufacturing or another highly regulated industry.
• Strong knowledge of GxP environments and validated systems.
• Experience with Computer System Validation (CSV), change control, data integrity and regulatory compliance.
• A proven track record of leading manufacturing or business systems supporting operational environments.
• Experience developing digital strategy, governance and transformation initiatives.
• Strong people leadership with experience building and developing high-performing teams.
• Excellent executive stakeholder management and influencing skills.
• Commercial experience managing suppliers, budgets and strategic vendor relationships.

• Pharmaceutical, biotechnology or medical device manufacturing.
• Manufacturing Systems, MES, LIMS, ERP or Operational Technology (OT).
• IT Service Management and Business Continuity Planning.
• ITIL, PRINCE2, PMP, Agile or similar professional certifications.

• Influence technology strategy at both site and regional level while supporting the manufacture of medicines that improve patients' lives.
• Senior leadership position with significant visibility across the business.
• Shape digital transformation within a global pharmaceutical organisation.
• Ownership of critical GxP-regulated systems supporting manufacturing operations.
• Exposure to regional and global technology initiatives.
• Lead a highly skilled multidisciplinary team in a collaborative culture focused on innovation, continuous improvement and patient outcomes.
• Hybrid working arrangement.