Postdoctoral Research Associate in Chromatin Biochemistry and Cancer Biology

Overview

A postdoctoral position is available in Dr. Hai Dao's lab. The Dao laboratory at the Department of Chemical Biology and Therapeutics is seeking a highly motivated postdoctoral research associate to conduct research at the interface of chromatin biology, cancer epigenetics, and chemical biology. Our team is dedicated to understanding the intricate molecular networks that regulate epigenetic processes in human cancers. We develop novel chemical probes, engineered enzymes, and synthetic chromatin platforms to dissect and manipulate chromatin-templated processes.

This position aims to understand the classic and elusive chromosomal species known as double minutes. Double minutes are extrachromosomal acentric chromatin bodies that are the hallmark of oncogenes in human cancers. Double minutes have a unique gene expression program and atypical chromosome segregation during mitosis; yet, the underlying mechanisms remain elusive. The goals are to elucidate the chromatin structure and associated factors of double minutes during interphase and metaphase to uncover the mechanisms underlying gene regulation and chromosome maintenance.

Your primary role as a postdoctoral researcher will be to develop independent research projects with the guidance of Dr. Hai Dao. You are expected to finish at least one project within three years. Additionally, you will have opportunities to get involved in collaborative projects, mentoring junior staffs and students. In addition to performing experiments, you will be expected to participate in writing your manuscripts and lab grants.

As part of the career development plan, you are encouraged to participate in relevant conferences and training courses.

Interested candidates should have a Ph.D. in chemical biology, biochemistry, or molecular biology. Preference will be given to applicants who have received their Ph.D. degrees within three years.

Required skill sets

• Chromatin biology/biochemistry

Preferred skill sets

• Epigenomic techniques
• Proteomics
• Cell imaging
• Biochemical and biophysical techniques
• Managing skills

St. Jude Children’s Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children. Our 300 faculty work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine.

St. Jude is ranked on Fortune Magazine’s “Best Workplaces in Health Care & Biopharma” and Glassdoor’s “Best Places to Work,” and is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food and culture.

We are in pursuit of the brightest minds in biomedical sciences, individuals poised to contribute to our research progress. Other than access to top-quality scientists and mentors, as a postdoctoral trainee e, you will have:

• A Blend of Academic Freedom and Industrial Efficiency
  :
  Access to shared resources and facilities led by expert scientists, coupled with cutting-edge technology, accelerates research productivity.

• Customized Professional and Career Growth: Experience specifically designed programs to enhance professional growth and career readiness empowering postdocs for success beyond their training. This includes access to grant writing workshops, individual development plans, teaching and mentoring opportunities, non-research career advancement programs, professional development allowance, and so much more.

• Competitive Compensation: Embark on your journey with a competitive salary starting at $72,500 a year, comprehensive benefits and generous relocation assistance, reflecting our commitment to recognize and invest in talent.

• A Sense of Community: St. Jude fosters a vibrant postdoc community that supports a well-balanced life. A dynamic environment promotes connections and camaraderie among postdocs from all backgrounds.

St. Jude is an Equal Opportunity Employer

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Jude.