Scientist, Research Scientist

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The University of Miami/UHealth Department of SCCC has an exciting opportunity for a Full Time Transgenic and Gene Targeting – Scientist to work at the UHealth campus in Miami, Florida.

The Scientist, SOM supports the University’s research goals and objectives by engaging in complex experiments and investigations in a range of areas, depending on specialty and interests. Moreover, an employee in this position contributes to the scientific community and promotes the University’s reputation as a leader in the field.

Oversees research employees, students, and other relevant staff. Authors scientific publications, technical and agency reports, and patent applications. Assists in the development of training materials for research staff. Plans experiment and records and analyzes findings. Prepares research proposals and funding applications. Ensures that all activities are in compliance with applicable quality and regulatory standards. Maintains current knowledge of relevant scientific and technical developments.

Presents ongoing work and findings to colleagues at academic conferences. Adheres to University and unit‑level policies and procedures and safeguards University assets.

Additional duties and responsibilities are not limited to the list below and may be expanded as necessary.

• Skill in collecting, organizing, and analyzing data.
• Ability to recognize, analyze, and solve a variety of problems.
• Ability to exercise sound judgment in making critical decisions.

• Education: Ph.D., M.D. or other doctoral level degree in relevant field.
• Experience: Minimum 10 years of relevant experience.
• Knowledge, Skills and Attitudes:
  • Skill in collecting, organizing, and analyzing data.
  • Ability to recognize, analyze, and solve a variety of problems.
  • Ability to exercise sound judgment in making critical decisions.

The Sylvester Comprehensive Cancer Center is currently seeking a Transgenic and Gene Targeting – Scientist who will join the Cancer Modeling Shared Resource. This translational Facility provides qualified, cost effective and state‑of‑the‑art services to foster cancer research advancements and accelerate the discovery of tailored antitumor therapies. We are seeking a dynamic individual who would like to participate in the creation and development of new service lines in a busy and fast‑paced environment, mainly focused on the generation of state‑of‑the‑art services necessary to generate novel mouse models of cancer using advanced techniques and technologies to produce and manipulate customized genetically engineered rodents.

This person will directly assist the Director in running and implementing these new genetic engineering services to support researchers in the field of functional genomics and disease modeling. The successful candidate will also participate in the planning and implementation of genome editing and transgenic projects including being responsible for the experimental design, procurement and validation of the services provided and models produced under the direction of Dr.

Bilbao.

Specific responsibilities of the position include and are not limited to:

• Ensure the implementation of the transgenic and genetic engineering services. These services include the use of CRISPR/Cas9 targeting to produce gene knockouts, conditional knockouts, single‑point mutations, and insertions and gene fusions, also simultaneously mutating multiple genes in a single experiment; transgenic mice generation by injecting plasmid or bacterial artificial chromosome DNA constructs into inbred and outbred mouse strains; knockout (KO) mice, conditional knockout (CKO) mice, knock‑in (KI) mice generation using traditional ES cell targeting including C57BL
  6 ESCs; ES cell, tetraploid and iPS cell…