RNA Chemical Biology Postdoctoral Fellow
Listed on 2026-10-28
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Research/Development
Research Scientist, Biomedical Science, Biology
Apply now Job no: 539984
Work type: Post Doc Associate
Location: Palm Beach
Categories: Biology/Life Science, Grant or Research Administration, Physical/Mathematical Sciences
Department: - SR-CHEM-DISNEY LAB
Classification
Title:
Postdoctoral Associate
Classification
Minimum Requirements:
Qualified applicants should have completed a relevant Ph.D. degree in structural biology, chemical biology, or organic/medicinal chemistry.
Job Description:
Effective immediately, the Disney group in the Department of Chemistry at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology ( (Use the "Apply for this Job" box below). ) is seeking to hire a Postdoctoral Associate in RNA Chemical Biology.
The Disney group is a chemical biology laboratory focused on developing rational approaches to design highly selective therapeutics from only genome sequence. Known for its prolific output and pioneering research culture, the group has furthered advancements in annotating RNA structure from sequence alongside several novel technologies created in-house. The laboratory’s targeting of RNA by small molecules, an ambitious and highly focused enterprise in pursuit of chemical probe and lead medicine development, is summarized in Nature Reviews Drug Discovery ): 169–179.
Other representative publications from the Disney group include:
• Studying disease mediated by RNA repeat expansions that cause genetically defined ALS and dementia:
o Science Translation Medicine (2021) 13:eabd
5991; doi: 10.1126/scitranslmed.abd
5991
o Cell Chemical Biology (2019) 26:179-190; doi: 10.1016/j.chembiol.
• Targeted RNA degradation and related technologies:
o Nature Reviews Drug Discovery ): 169–179;doi: 10.1038/s-8
o Journal of the American Chemical Society (2021) 143:; doi: 10.1021/jacs.
1c02248
o Science Translation Medicine (2021) 13:eabd
5991; doi: 10.1126/scitranslmed.abd
5991
o Proceedings of the National Academy of Sciences USA (2020) 117:; doi: 10.1073/pnas.
o Proceedings of the National Academy of Sciences USA (2019) 116:; doi: 10.1073/pnas.
o Journal of the American Chemical Society (2018) 140:; doi: 10.1021/jacs.
8b01233
o Nature Chemical Biology (2017) 13:188-193; doi: 10.1038/nchembio.
225
• Precision targeted therapeutics for difficult-to-treat cancers and other diseases:
o Journal of the American Chemical Society (2019) 141:; doi: 10.1021/jacs.
8b10558
o Cell Chemical Biology (2018) 25:; doi: 10.1016/j.chembiol.
o Proceedings of the National Academy of Sciences USA (2016) 113:; doi: 10.1073/pnas.
o Proceedings of the National Academy of Sciences USA (2020) 117:; doi: 10.1073/pnas.
Our Commitment:
The Disney group is highly committed to each individual’s professional development during his or her time in the lab. A high impact research project and training plan to support the achievement of short-term as well as long-term career goals is customized for each student.
Commensurate with experience.
Required Qualifications:
Qualified applicants should have completed a relevant Ph.D. degree in structural biology, chemical biology, or organic/medicinal chemistry.
Preferred:
Preference will be given to candidates with strong skills in RNA biology techniques, molecular biology, and biochemical methods. Previous experience with RNA-seq data analysis, DNA encoded library design and screening, and structure-based design is also desirable.
Highly motivated candidates possessing a strong academic track-record, a high-impact publication list, a team-player mentality, and an interest in targeting the RNA world are poised for success in the group.
The Disney group employs a broad range of experimental techniques, and thus a wide set of research skills is preferable, and a willingness to learn new methods is essential.
Special Instructions to Applicants:
In…
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