Principal Product Development Scientist

Overview

Shape the Future of Process Analytics at Waters Join a team developing next-generation LC/MS-based Process Analytical Technology (PAT) solutions that are transforming bioprocess monitoring and control. In this highly visible role, you will lead the hands-on development, integration and deployment of integrated sample preparation and LC/LC-MS systems, taking technologies from feasibility and early development through verification and pre-commercial deployment. Combining systems development, experimental design and systems thinking, you will translate customer and workflow needs into technical requirements, resolve technical uncertainty, and troubleshoot multidisciplinary systems spanning fluidics, hardware, software and informatics.

As a Principal technical leader, you will provide cross-functional technical direction and support strategic customer evaluations and deployments, including installation, troubleshooting and root-cause investigation. Approximately 40% travel may be required.

Responsibilities

Lead hands-on development, integration and early deployment of sample preparation and LC/LC-MS systems, from feasibility and prototypes through verification and pre-commercial deployment. Design and execute hypothesis-driven experiments to establish technical feasibility, resolve uncertainty, characterize system performance and guide design decisions. Translate customer, user and workflow needs into measurable system requirements, including functional, interface and performance requirements with appropriate acceptance criteria. Lead multidisciplinary system integration and troubleshooting across sample preparation, fluidics, LC/LC-MS instrumentation, mechanical and electrical hardware, software and informatics, using experimental evidence to establish root cause.

Define system architecture, interfaces, critical parameters and integration strategies, providing technical direction and constructively challenging design assumptions through scientific and engineering evidence. Lead system verification and technical risk activities, including test strategy, design reviews, FMEAs, risk assessments and investigation of system performance issues. Own key technical documentation, including system requirements, specifications, interface definitions, test protocols, technical assessments and formal reports.

Provide hands-on technical support at strategic customer sites, including installation, evaluation, troubleshooting and root-cause investigation of alpha, beta and pre-commercial systems, with learning fed back into system requirements and design. Approximately 40% travel may be required.

Qualifications

BS, MS, or PhD in Chemistry, Physics, Engineering, or a related scientific field. Strong hands-on LC or LC-MS experience, with the analytical depth to assess integrated system performance. Experience developing instruments or integrated analytical systems, including feasibility, early development and system integration. Ability to translate customer and workflow needs into measurable system, functional, interface and performance requirements. Hands-on experience integrating and troubleshooting multidisciplinary systems spanning sample preparation, fluidics, LC/LC-MS, hardware, software and informatics.

Demonstrated ability to investigate complex technical problems using hypothesis-driven experimentation and root-cause analysis. Strong technical leadership and authorship, with experience influencing cross-functional teams and producing requirements, specifications, test documentation and technical reports. Experience in bioprocess analytics, PAT, or biopharmaceutical applications is highly desirable.

Company Description

Waters Corporation (NYSE:WAT)  is a global leader in life sciences and diagnostics, dedicated to accelerating the benefits of pioneering science through analytical technologies, informatics, and service. With a focus on regulated, high-volume testing environments, our innovative portfolio harnesses deep scientific expertise across chemistry, physics, and biology. We collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance.

Through a shared culture of relentless innovation, our passionate team of ~16,000 colleagues turn scientific challenges into breakthroughs that improve lives worldwide.
Diversity…