Clinical Research Nurse C​/D; Abramson Cancer Center

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Clinical Research Nurse C/D (Abramson Cancer Center)

Clinical Research Nurse C

The Abramson Cancer Center at Pennsylvania Hospital’s Clinical Research Unit seeks a full-time, Clinical Research Nurse (CRN) to conduct studies involving a wide variety of investigational products and various sponsors. This position will report directly to the Research Manager and work directly with Physician Investigators (“PI”) on clinical research performed. This area of research requires dedicated attention and care to ensure subject safety and well-being.

The successful candidate will comply with all policies relating to UPHS, JCAHO, GCP and other regulatory standards.

Job Responsibilities

Clinical Research Nurse C Responsibilities

• Work in collaboration with Research Team Leaders and Principal Investigators with initiating study procedures for new IITs and industry-sponsored clinical trials. Manage all aspects of Phase I – IV clinical trials. Participate in the conduct of audits by study sponsors, CROs, the FDA, the Eastern Oncology Group, the University of Pennsylvania’s CTSRMC, and other groups.
• Work directly with physicians to design, set-up and execute clinical trials. May be required to speak at investigator meetings or site initiation visits for investigator-initiated trials (“IITs”) where physician is the national PI. Assist in analyzing data to determine response and clinical outcomes; assist with literature reviews; contribute to preparation of study abstracts, posters, manuscripts and grant applications.
• Develop and maintain ongoing communication with the clinical teams including, but not limited to laboratory, infusion, radiology, Advanced Practitioners, triage, inpatient and pharmacy. Provide in-service and support to infusion, infusion pharmacy, inpatient staff as appropriate. Provide ongoing service education updates to all investigators and PAH/HUP staff that have eligible participants for clinical research trials
• Care for subjects in all age groups from young adult through geriatrics. Coordinate activities of oncology team in caring for subjects. Administer or provide oversight of administration of medications, chemotherapeutic drugs, biologic response modifiers, cellular immunotherapies and other treatment agents or study interventions, as appropriate.
• Review all clinical and laboratory data and adverse events, reporting in real-time to the Principal Investigator (PI) for assessment and review, and communicate with medical staff regarding protocol-specific management of toxicities and adverse events.
• Triage any questions subjects may have regarding protocol specifics, investigational products, lab results, effects of therapies, medications, and symptom…