Clinical Research Nurse C​/D; Abramson Cancer Center

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Clinical Research Nurse C/D (Abramson Cancer Center)

Clinical Research Nurse C

The Abramson Cancer Center at Pennsylvania Hospital’s Clinical Research Unit seeks a full-time Clinical Research Nurse (CRN) to conduct studies involving investigational products and various sponsors. This position reports to the Research Manager and works directly with Physician Investigators on clinical research. The candidate must comply with UPHS, JCAHO, GCP, and other regulatory standards.

Job Responsibilities

Clinical Research Nurse C Responsibilities

• Collaborate with Research Team Leaders and Principal Investigators to initiate study procedures for new IITs and industry-sponsored clinical trials. Manage all aspects of Phase I – IV trials. Participate in audits by sponsors, CROs, the FDA, the Eastern Oncology Group, the University of Pennsylvania’s CTSRMC, and others.
• Design, set up, and execute clinical trials with physicians. May speak at investigator meetings or site initiation visits for IITs where the physician is the PI. Assist in data analysis, literature reviews, and preparation of abstracts, posters, manuscripts, and grant applications.
• Maintain ongoing communication with clinical teams (laboratory, infusion, radiology, Advanced Practitioners, triage, inpatient, pharmacy). Provide in-service and support to infusion staff and study participants; offer education updates to investigators and PAH/HUP staff with eligible participants.
• Care for subjects across all ages from young adult to geriatrics. Coordinate oncology team activities and oversee administration of medications, chemotherapeutic drugs, biologic modifiers, cellular immunotherapies, and other treatment agents as appropriate.
• Review clinical and laboratory data and adverse events in real time with the PI; communicate protocol-specific management of toxicities to medical staff.
• Address protocol questions, investigational products, lab results, and symptoms within the clinical scope, referring questions to the PI or medical team as needed.
• Collect, review, and report study data within the timelines specified by the Clinical Trials Agreement. May include transporting specimens and submitting documents to IRB, CTSRMC, IBC, CHPS for approvals and amendments.
• Provide coverage and support to other research nurses and coordinators to meet staffing needs.
• Possess a variable schedule; research subjects may be seen in early morning/evening hours and some travel may be required.

Qualifications

• Registered Nurse licensed in Pennsylvania without restriction. Bachelor’s degree with 2–3 years of relevant experience, or equivalent combination of education and experience. Oncology experience strongly preferred. Clinical research experience preferred but not required. BSN preferred.

Clinical Research Nurse D Responsibilities

The Clinical Research Nurse D will have the same duties as C with the following:

• Work independently with minimal supervision; may lead or back up the supervisor.
• Design, set up, and execute studies. May be responsible for investigator-initiated IND/IDE trials with faculty supervision. Present at investigator meetings or site initiation visits for IITs where the PI is the collaborating physician. Analyze data and contribute to abstracts, posters, manuscripts, and grants.
• Independently manage complex trials and registries within the Pennsylvania Hospital Research Team. Supervise non-licensed…